Age-associated mosaicism and polyploidy in Down's syndrome

dc.contributorUniversidade Federal de São Paulo (UNIFESP)
dc.creatorBorsatto, B.
dc.creatorArruda, M. de
dc.creatorSmith, C.
dc.creatorGarcez, EMDM
dc.creatorPeres, C. A.
dc.date.accessioned2016-01-24T12:30:32Z
dc.date.accessioned2022-10-07T21:11:23Z
dc.date.available2016-01-24T12:30:32Z
dc.date.available2022-10-07T21:11:23Z
dc.date.created2016-01-24T12:30:32Z
dc.date.issued1998-01-12
dc.identifierMechanisms of Ageing and Development. Clare: Elsevier Sci Ireland Ltd, v. 100, n. 1, p. 77-83, 1998.
dc.identifier0047-6374
dc.identifierhttp://repositorio.unifesp.br/handle/11600/25855
dc.identifier10.1016/S0047-6374(97)00122-X
dc.identifierWOS:000072099300008
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/4027448
dc.description.abstractAge-related increases in the frequencies of cells with chromosome 21 loss and of polyploid cells were documented in short-term peripheral blood lymphocyte cultures from 54 patients with Down's syndrome (DS), ages 0 to 48 years. the polyploid data, together with previous work from this laboratory with non-DS subjects, suggest that this may be a useful indicator of aging in lymphocytes. (C) 1998 Elsevier Science Ireland Ltd.
dc.languageeng
dc.publisherElsevier B.V.
dc.relationMechanisms of Ageing and Development
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.rightsAcesso restrito
dc.subjectDown's syndrome
dc.subjectchromosome 21
dc.subjectaging
dc.subjectpolyploidy
dc.subjectPoisson regression
dc.titleAge-associated mosaicism and polyploidy in Down's syndrome
dc.typeArtigo


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