dc.contributor | Universidade Federal de São Paulo (UNIFESP) | |
dc.creator | Bordin, Jose Orlando [UNIFESP] | |
dc.creator | Souzapinto, J. C. | |
dc.creator | Kerbauy, José [UNIFESP] | |
dc.date.accessioned | 2018-06-15T14:28:02Z | |
dc.date.accessioned | 2022-10-07T21:10:43Z | |
dc.date.available | 2018-06-15T14:28:02Z | |
dc.date.available | 2022-10-07T21:10:43Z | |
dc.date.created | 2018-06-15T14:28:02Z | |
dc.date.issued | 1991-01-01 | |
dc.identifier | Brazilian Journal Of Medical And Biological Research. Sao Paulo: Assoc Bras Divulg Cientifica, v. 24, n. 9, p. 895-899, 1991. | |
dc.identifier | 0100-879X | |
dc.identifier | http://repositorio.unifesp.br/11600/43009 | |
dc.identifier | WOS:A1991GL87500004 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/4027344 | |
dc.description.abstract | The enzyme-linked antiglobulin test (ELAT) was employed to measure the number of IgG molecules per red blood cell (IgG/RBC) in 11 patients with autoimmune hemolytic anemia (AIHA). All patients with AIHA had high levels of red cell- associated IgG (110-3,650 IgG/RBC). The control group consisted of normal volunteers (N = 10) and patients with hereditary spherocytosis (N = 1), beta-degree-thalassemia (N = 1), immunologic thrombocytopenic purpura (N = 3) and IgG multiple myeloma (N = 4). All control individuals presented low levels of red cell IgG (less than 38 IgG/RBC) with the exception of one of four patients with myeloma who had a mildly elevated value (50 IgG/RBC). Since the multiple myeloma patients had > 2g/dl IgG, the possible nonspecific uptake of IgG onto the RBCs of patients with elevated serum IgG values did not interfere with the results of ELAT. ELAT proved to be a useful method for accurate quantification of the amount of IgG specifically bound on the surface of RBC of patients with AIHA. | |
dc.language | eng | |
dc.publisher | Assoc Bras Divulg Cientifica | |
dc.relation | Brazilian Journal Of Medical And Biological Research | |
dc.rights | Acesso restrito | |
dc.subject | AUTOIMMUNE HEMOLYTIC ANEMIA | |
dc.subject | ENZYME-LINKED ANTIGLOBULIN TEST | |
dc.subject | ELAT | |
dc.subject | COOMBS TEST | |
dc.subject | IGG | |
dc.title | MEASUREMENT OF RED-BLOOD-CELL ANTIBODIES IN AUTOIMMUNE HEMOLYTIC-ANEMIA | |
dc.type | Artigo | |