Experimental model of facial paralysis by nerve compression in primates (Callithrix sp.): A new model of facial paralysis in small nonhuman primates

dc.contributorUniversidade Federal de São Paulo (UNIFESP)
dc.creatorNeiva, Felipe Costa [UNIFESP]
dc.creatorBorin, Andrei [UNIFESP]
dc.creatorCinini, Simone [UNIFESP]
dc.creatorMello, Luiz Eugenio A. M. [UNIFESP]
dc.creatorCruz, Oswaldo Laercio M. [UNIFESP]
dc.creatorTesta, Jose Ricardo G. [UNIFESP]
dc.date.accessioned2016-01-24T14:27:59Z
dc.date.accessioned2022-10-07T21:09:37Z
dc.date.available2016-01-24T14:27:59Z
dc.date.available2022-10-07T21:09:37Z
dc.date.created2016-01-24T14:27:59Z
dc.date.issued2012-11-01
dc.identifierActa Oto-laryngologica. London: Informa Healthcare, v. 132, n. 11, p. 1239-1242, 2012.
dc.identifier0001-6489
dc.identifierhttp://repositorio.unifesp.br/handle/11600/35492
dc.identifier10.3109/00016489.2012.697639
dc.identifierWOS:000309751800017
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/4027159
dc.description.abstractConclusion: We conclude that facial nerve injury induced by compression is associated with a reasonable time window (4 weeks) that allows possible neurotrophic effects to be analyzed. Additionally, there are no hints of cross-innervation by the contralateral facial nerve or parallel innervation by other nerves in the hemiface ipsilateral to the injured nerve. Objective: the aim of this work was to develop an experimental model of facial nerve injury in nonhuman primates (Callithrix sp.). Methods: in this study, individuals of the non-human primate species Callithrix sp. were subjected to three different types of facial nerve injury, and they were observed for 27 days after surgery by video to record their facial movements. Results: Two types of nerve compression caused severe initial facial paralysis followed by gradual recovery until normal levels were reached at the end of the evaluation period. Injury induced by nerve resection was followed by a complete lack of facial movement recovery.
dc.languageeng
dc.publisherInforma Healthcare
dc.relationActa Oto-laryngologica
dc.rightshttp://informahealthcare.com/userimages/ContentEditor/1255620309227/Copyright_And_Permissions.pdf
dc.rightsAcesso restrito
dc.subjectFacial nerve
dc.subjectnerve regeneration
dc.subjectanimal models
dc.subjectneurology
dc.subjectcranial nerve diseases
dc.subjectcranial nerves
dc.subjectnerve degeneration
dc.titleExperimental model of facial paralysis by nerve compression in primates (Callithrix sp.): A new model of facial paralysis in small nonhuman primates
dc.typeArtigo


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