Genetic control of natural resistance of mouse macrophages to Coxiella burnetii infection in vitro: Macrophages from restrictive strains control parasitophorous vacuole maturation

dc.contributorUniversidade Federal de São Paulo (UNIFESP)
dc.creatorZamboni, Dario Simões [UNIFESP]
dc.date.accessioned2016-01-24T12:37:04Z
dc.date.accessioned2022-10-07T20:59:35Z
dc.date.available2016-01-24T12:37:04Z
dc.date.available2022-10-07T20:59:35Z
dc.date.created2016-01-24T12:37:04Z
dc.date.issued2004-04-01
dc.identifierInfection and Immunity. Washington: Amer Soc Microbiology, v. 72, n. 4, p. 2395-2399, 2004.
dc.identifier0019-9567
dc.identifierhttp://repositorio.unifesp.br/handle/11600/27685
dc.identifierWOS000220481600065.pdf
dc.identifier10.1128/IAI.72.4.2395-2399.2004
dc.identifierWOS:000220481600065
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/4025772
dc.description.abstractMacrophages from A/J and BALB/c mice were more susceptible to Coxiella burnetti phase II infection than were those from C57BL/6, C57BL/10, B10.A, C3H/HePas, and Swiss mice. Resistant macrophages effectively controlled the development of large replication vacuoles (LRVs), which accounted for the restriction of bacterial multiplication within the cultures. However, compared to fibroblasts, all macrophages controlled bacterial multiplication within LRVs.
dc.languageeng
dc.publisherAmer Soc Microbiology
dc.relationInfection and Immunity
dc.rightsAcesso aberto
dc.titleGenetic control of natural resistance of mouse macrophages to Coxiella burnetii infection in vitro: Macrophages from restrictive strains control parasitophorous vacuole maturation
dc.typeArtigo


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