Artigo
Efficient and eco-friendly synthesis of iodinated aromatic building blocks promoted by iodine and hydrogen peroxide in water: a mechanistic investigation by mass spectrometry
Fecha
2012-10-03Registro en:
Tetrahedron Letters. Oxford: Pergamon-Elsevier B.V., v. 53, n. 40, p. 5372-5375, 2012.
0040-4039
10.1016/j.tetlet.2012.07.102
WOS:000309087100005
Autor
Gallo, Rafael D. C.
Ferreira, Irlon M.
Casagrande, Gleison A.
Pizzuti, Lucas
Oliveira-Silva, Diogo [UNIFESP]
Raminelli, Cristiano [UNIFESP]
Institución
Resumen
The reaction of aromatic and heteroaromatic compounds with molecular iodine in the presence of aqueous hydrogen peroxide using water without any co-solvent at 50 degrees C for 24 h produced versatile iodinated organic molecules with potential application in organic synthesis and medicine in very good yields. in addition, a mechanistic investigation for the iodination process was carried out by mass spectrometry. (C) 2012 Elsevier B.V. All rights reserved.