dc.contributor | Universidade Federal de São Paulo (UNIFESP) | |
dc.creator | Souza, Marilia Rodrigues Freitas de [UNIFESP] | |
dc.creator | Toledo, Carlos Fischer de [UNIFESP] | |
dc.creator | Borges, Durval Rosa [UNIFESP] | |
dc.date.accessioned | 2018-06-15T17:17:24Z | |
dc.date.accessioned | 2022-10-07T20:49:33Z | |
dc.date.available | 2018-06-15T17:17:24Z | |
dc.date.available | 2022-10-07T20:49:33Z | |
dc.date.created | 2018-06-15T17:17:24Z | |
dc.date.issued | 2000-10-01 | |
dc.identifier | Digestive Diseases And Sciences. Dordrecht: Springer, v. 45, n. 10, p. 1964-1970, 2000. | |
dc.identifier | 0163-2116 | |
dc.identifier | http://repositorio.unifesp.br/11600/43492 | |
dc.identifier | 10.1023/A:1005535808464 | |
dc.identifier | WOS:000165435500011 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/4023471 | |
dc.description.abstract | Sufferers of schistosomiasis mansoni can evolve a clinical form of the disease associated with portal hypertension. To differentiate this form, routine clinical tests and biological indices were evaluated. In all, 54 HBsAg- and HCV-negative patients were studied, 42 with schistosomiasis and 12 normal volunteers. Using clinical criteria, ultrasonography, and endoscopy, the schistosomiasis patients were classified into two groups: mild chronic form (MS, N = 14) and chronic form associated with portal hypertension (PH, N = 28). The laboratory parameters of the MS group did not differ from the controls. The PH group differed from the others in prothrombin index, thrombocytemia, gamma -glutamyltransferase, serum alpha (2)-macroglobulin, and the calculated indices. ROC plot cutoff levels verified that isolated thrombocytemia was the most efficient marker for discrimination of the PH and MS forms. Thrombocytemia of 130 x 10(9) platelets/liter discriminated the groups with an 86% accuracy when all patients were analyzed and 96% when only schistosomiasis patients who did not consume alcohol were included. | |
dc.language | eng | |
dc.publisher | Springer | |
dc.relation | Digestive Diseases And Sciences | |
dc.rights | http://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0 | |
dc.rights | Acesso aberto | |
dc.subject | platelets | |
dc.subject | schistosomiasis | |
dc.subject | portal hypertension | |
dc.subject | hypersplenism | |
dc.title | Thrombocytemia as a predictor of portal hypertension in schistosomiasis | |
dc.type | Artigo | |