dc.contributorUniversidade Federal do Rio de Janeiro (UFRJ)
dc.contributorUniversidade Federal de São Paulo (UNIFESP)
dc.contributorUniversidade Federal Fluminense (UFF)
dc.contributorFiocruz MS
dc.creatorSouza, Gisele
dc.creatorDolinsky, Manoela [UNIFESP]
dc.creatorMatos, Andrea
dc.creatorChagas, Cristiane
dc.creatorRamalho, Andrea
dc.date.accessioned2016-01-24T14:39:58Z
dc.date.accessioned2022-10-07T20:36:42Z
dc.date.available2016-01-24T14:39:58Z
dc.date.available2022-10-07T20:36:42Z
dc.date.created2016-01-24T14:39:58Z
dc.date.issued2015-02-01
dc.identifierArchives of Gynecology and Obstetrics. Heidelberg: Springer Heidelberg, v. 291, n. 2, p. 319-325, 2015.
dc.identifier0932-0067
dc.identifierhttp://repositorio.unifesp.br/handle/11600/38675
dc.identifier10.1007/s00404-014-3404-4
dc.identifierWOS:000348145800016
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/4020051
dc.description.abstractTo evaluate vitamin A concentration in mature breast milk of nursing mothers aiming to meet the daily needs and the formation of liver reserve in pre-term (PT) and term infants (T) in comparison with the recommended intake for this nutrient in this group.We analyzed the retinol concentration in the milk of 120 nursing mothers (40 of PT infants and 80 of T infants) by collecting 10 mL of mature breast milk, held by a hand spray of one of the breasts 2 h after the last feeding in the morning. the cutoff points adopted for identification of vitamin A deficiency (VAD) and the liver reserve were < 1.05 and > 2.3 mu mol/L, respectively.The concentrations of retinol in the human milk of T infants were superior to concentrations in the milk of PT infants (1.87 + 0.81 > 1.38 + 0.67 mu mol/L, p < 0.0001). They were higher in T compared to PT (352.64 + 152.72 > 217.65 + 105.65 mu g, p < 0.0001), but both were below the recommendation. VAD was 20.0 % (T) and 27.5 % (PT). Only 40.0 % (T) and 22.5 % (PT) of the mothers had retinol concentrations in milk above 2.3 mmol/L.The milk of the nursing mothers studied did not have enough retinol to meet the daily needs and to form liver reserve in both groups, especially in PT newborns. This finding reinforces the idea that supplementation with massive doses of vitamin A in the immediate postpartum period can be used as a protective device of the infant against VAD.
dc.languageeng
dc.publisherSpringer
dc.relationArchives of Gynecology and Obstetrics
dc.rightshttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.rightsAcesso restrito
dc.subjectVitamin A
dc.subjectHuman milk
dc.subjectPre-term
dc.subjectTerm
dc.subjectLiver reserve
dc.titleVitamin A concentration in human milk and its relationship with liver reserve formation and compliance with the recommended daily intake of vitamin A in pre-term and term infants in exclusive breastfeeding
dc.typeArtigo


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