Artigo Publicado em Periódico
One-pot and catalyst-free synthesis of thiosemicarbazones via multicomponent coupling reactions
Fecha
2009Registro en:
0040-4039
v. 50, n. 18
Autor
Cunha, Silvio do Desterro
Silva, Tiago Lima da
Cunha, Silvio do Desterro
Silva, Tiago Lima da
Institución
Resumen
A novel and efficient procedure for the synthesis of thiosemicarbazones has been achieved via a multicomponent and catalyst-free reaction of phenyl or p-chlorophenyl isothiocyanate, hydrazine, and aldehydes or ketones. The method afforded 20 thiosemicarbazones in good yields and short reaction time.