Cytogenetic effects of malathion insecticide on somatic and germ cells of mice

dc.creatorSalvadori, D. M. F.
dc.creatorRibeiro, L. R.
dc.creatorPereira, Carlos Alberto Braganfa
dc.creatorBeçak, Willy
dc.creatorSalvadori, D. M. F.
dc.creatorRibeiro, L. R.
dc.creatorPereira, Carlos Alberto Braganfa
dc.creatorBeçak, Willy
dc.date.accessioned2013-02-05T20:56:03Z
dc.date.accessioned2022-10-07T16:18:29Z
dc.date.available2013-02-05T20:56:03Z
dc.date.available2022-10-07T16:18:29Z
dc.date.created2013-02-05T20:56:03Z
dc.date.issued1988
dc.identifierhttp://www.repositorio.ufba.br/ri/handle/ri/8380
dc.identifierv. 204, n. 2
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/4007077
dc.description.abstractMale mice dermally exposed to single or multiple treatment (5 days/2 weeks) showed that the ability of malathion to induce chromosome aberrations in somatic (bone marrow) and germ cells (primary spermatocytes) was related to the type of treatment and dose used. Statistically significant increases of chromosome aberrations in bone marrow cells occurred after single treatment (500 and 2000 mg/kg body wt) when chromatid gaps were included and after multiple treatment (250 and 500 mg/kg) when they were excluded. No dose—response relationships were observed for either treatment. In germ cells, malathion induced a significant increase of univalents in both types of treatment but structural chromosome aberrations were induced only by multiple treatment. Malathion induced a significant decrease of the mitotic indices in the bone marrow.
dc.languageen
dc.publisherMutation Research/Genetic Toxicology
dc.sourcehttp://dx.doi.org/10.1016/0165-1218(88)90101-2
dc.subjectMalathion
dc.subjectChromosome aberration
dc.subjectMouse
dc.subjectAbnormalities
dc.titleCytogenetic effects of malathion insecticide on somatic and germ cells of mice
dc.typeArtigo de Periódico


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