masterThesis
Mantas de fibras poliméricas biodegradáveis obtidas por Solution Blow Spinning como modelo biomimético de casulos de Rostchildia sp.
Fecha
2021-01-29Registro en:
ALMEIDA, Carolina Lima de. Mantas de fibras poliméricas biodegradáveis obtidas por Solution Blow Spinning como modelo biomimético de casulos de Rostchildia sp. 2021. 90f. Dissertação (Mestrado em Ciência e Engenharia de Materiais) - Centro de Ciências Exatas e da Terra, Universidade Federal do Rio Grande do Norte, Natal, 2021.
Autor
Almeida, Carolina Lima de
Resumen
There has been great interest in the study of biomimetics for several fields of
science, such as medical applications. In this work, biodegradable polymeric fiber
mats were produced with properties compatible with those found in cocoons of the
moth Rothschildia sp. Initially, the cocoon was studied using techniques of
thermogravimetry (TG), differential scanning calorimetry (DSC), Fourier transform
infrared spectroscopy (FTIR), scanning electron microscopy (SEM) and mechanical
tensile tests. The results indicated a structure composed of fibroin fibers in a sericin
matrix, in addition to hydroxyapatite. The mats were produced from polycaprolactone
(PCL) and poly (lactic acid) (PLA) fibers, which have a chemical structure
comparable to fibroin, with the addition of hydroxyapatite (HA). Solution Blow
Spinning (SBS) technique was used to produce the polymeric fibers with a multinozzle matrix and a rotating collector. After the spinning process, the mats were hot
pressed, with processing temperature and number of layers varying in five groups, to
form a PCL matrix and produce a structure equivalent to that of the cocoon. The
mats were also characterized by DSC, FTIR, SEM and mechanical tensile tests. The
chemical composition of the PCL and PLA mats were equivalent to that found in the
cocoon, as well as fibrous morphology resulting from the SBS processing. SEM
images confirmed the formation of a PCL matrix phase that binds the PLA fibers after
the hot press processing. Tensile strength of the mats varied according to the
number of layers and processing temperature used. The best results were obtained
for mats with six layers of PCL and PLA with the addition of HA, processed in a hot
press at 90 ° C, for 30 min. Although the strength of the mats produced were lower
than that of the cocoon, the results indicated that this material has a potential to be
used in biological media.