dc.contributor | Pereira, Hallissa Simplicio Gomes | |
dc.contributor | | |
dc.contributor | | |
dc.contributor | Barboza, Carlos Augusto Galvão | |
dc.contributor | | |
dc.contributor | Santos, Patricia Bittencourt Dutra dos | |
dc.contributor | | |
dc.creator | Moreno, Mariana Cabral | |
dc.date.accessioned | 2019-11-28T21:19:21Z | |
dc.date.accessioned | 2022-10-06T13:35:53Z | |
dc.date.available | 2019-11-28T21:19:21Z | |
dc.date.available | 2022-10-06T13:35:53Z | |
dc.date.created | 2019-11-28T21:19:21Z | |
dc.date.issued | 2019-07-04 | |
dc.identifier | MORENO, Mariana Cabral. Efeito da cafeína na movimentação ortodôntica e no comportamento de ratos: estudo experimental in vivo. 2019. 57f. Dissertação (Mestrado em Ciências Odontológicas) - Centro de Ciências da Saúde, Universidade Federal do Rio Grande do Norte, Natal, 2019. | |
dc.identifier | https://repositorio.ufrn.br/jspui/handle/123456789/28071 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/3970963 | |
dc.description.abstract | OBJECTIVE: To verify the effect of caffeine on orthodontic movement (MO) and
behavior of rats. METHODS: In this randomized in vivo experimental study, 12
healthy male Wistar rats (Rattus norvegicus albinus), 7-12 weeks, 200-300g were
used. These animals were submitted to OM (closed NiTi spring (50cN) between 1st
molar and upper incisors / left side) and daily administration of caffeine (3g / L) and
water by gavage for 21 consecutive days. The sample was divided into two groups: a)
control (n = 7): submitted to OM and water; b) experimental (n = 5): submitted to OM
and caffeine. The amount of OM was verified by a dry point compass and millimeter
ruler at the beginning and end times. The open field test was used in the four-stage
behavioral assessment: baseline (T0), after spring placement (T1), after 2nd gavage
(T2), after 21 days (T3). Then, Mann-Whitney statistical tests (amount of OM) and
Friedman test / Wilcoxon test (behavior) were performed at a significance level of 5%.
RESULTS: Caffeine did not interfere with OM (p> 0.05). Regarding the open field
test, statistically significant values (p> 0.05) were identified in several parameters.
CONCLUSION: Caffeine did not influence the amount of macroscopic orthodontic
movement, despite exhibiting anxiogenic effect on rat behavior. | |
dc.publisher | Brasil | |
dc.publisher | UFRN | |
dc.publisher | PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS ODONTOLÓGICAS | |
dc.rights | Acesso Aberto | |
dc.subject | Ortodontia | |
dc.subject | Técnicas de movimentação dentária | |
dc.subject | Ratos | |
dc.title | Efeito da cafeína na movimentação ortodôntica e no comportamento de ratos: estudo experimental in vivo | |
dc.type | masterThesis | |