dc.contributor | Pontes, Ana Cristina Facundo de Brito | |
dc.contributor | | |
dc.contributor | | |
dc.contributor | Silva, Francisco Ordelei Nascimento da | |
dc.contributor | | |
dc.contributor | Machado, Sérgio de Paula | |
dc.contributor | | |
dc.creator | Sousa Júnior, Francimar Lopes de | |
dc.date.accessioned | 2018-08-02T23:08:26Z | |
dc.date.accessioned | 2022-10-06T13:25:12Z | |
dc.date.available | 2018-08-02T23:08:26Z | |
dc.date.available | 2022-10-06T13:25:12Z | |
dc.date.created | 2018-08-02T23:08:26Z | |
dc.date.issued | 2018-02-05 | |
dc.identifier | SOUSA JÚNIOR, Francimar Lopes de. Desenvolvimento de novos complexos de cobre com derivados fenantrolínicos e isoniazida. 2018. 105f. Dissertação (Mestrado em Química) - Centro de Ciências Exatas e da Terra, Universidade Federal do Rio Grande do Norte, Natal, 2018. | |
dc.identifier | https://repositorio.ufrn.br/jspui/handle/123456789/25662 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/3968394 | |
dc.description.abstract | Imidazole [4,5-f] derivatives of 1-10-phenanthroline-5,6-dione (phendiona) are of
great importance in bioinorganic because of their biological properties, such as DNA
cleavage and its antibacterial potential, as well as its synthetic versatility, it allows the
inclusion of groups that will enhance its biochemical characteristics. In this context, the
present work has the objective of synthesizing and characterizing new copper complexes
with phenanthroline derivatives having isoniazid (INH) as an additional ligand. Thus,
[Cu(L)Cl2] and [Cu(L)(INH)2]Cl2, where synthesized L being phend and imidazole
derivatives obtained from the phend reaction with 4-cyanobenzaldehyde and 4-
nitrobenzaldehyde, referenced to L-CN and L-NO2. Ligands and complexes were
synthesized from adapted methodologies based on similar compounds described in the
literature and characterized by spectroscopic (Uv-Vis, IV and Raman) and
electrochemical techniques. The vibrational spectra it was possible to verify the C=O
stretches of the phend ligand and the main modes of the imidazole present in the ligands
L-CN and L-NO2, in addition, it was possible to determine that INH ligand was
coordinated bidentately. The electron spectra in DMSO showed the intraligant bands in
the region of 200 to 400 nm and the d-d transitions in 767, 741 and 732 nm for the
complexes [Cu(phend)Cl2], [Cu(L-CN)Cl2] and [Cu(L-NO2)Cl2] respectively. For
complexes with a INH ligand as d-d bands were observed in the regions 760, 721 and 719
nm for [Cu(phend)(INH)2]Cl2, [Cu(L-CN)(INH)2]Cl2 and [Cu(L-NO2)(INH)2]Cl2
respectively, moreover, the following relationship was found ligand field unfolding Cl- <
INH < phend < L-CN < L-NO2. The fluorescence, it was possible to observe the emission
of the compounds in the region of 450 to 565 nm, as well as a relation of the energies of
the emission bands with the receptor character of the ligands. In addition, the cyclic
voltammograms of [Cu(L)Cl2] complexes showed just the one redox pair indicative of
the Cu2+/Cu+
process, however, with the replacement of the chlorides by INH it was
possible to verify two redox pairs Cu2+/Cu+
and Cu+
/Cu0
processes. | |
dc.publisher | Brasil | |
dc.publisher | UFRN | |
dc.publisher | PROGRAMA DE PÓS-GRADUAÇÃO EM QUÍMICA | |
dc.rights | Acesso Aberto | |
dc.subject | Complexos de cobre | |
dc.subject | Derivados imidazólicos | |
dc.subject | Isoniazida | |
dc.title | Desenvolvimento de novos complexos de cobre com derivados fenantrolínicos e isoniazida | |
dc.type | masterThesis | |