bachelorThesis
Etnofarmacologia, fitoquímica, propriedades terapêuticas e toxicidade do gênero Turnera (Passifloraceae): uma revisão sistemática
Fecha
2019-11-06Registro en:
AZEVEDO, Rebeca Gondim Cabral Medeiros de .Etnofarmacologia, Fitoquímica, propriedades terapêuticas e toxicidade do gênero Turnera (Passifloraceae): uma revisão sistemática. 2019. 46f. Trabalho de Conclusão de Curso (Graduação em Farmácia) - Departamento de Farmácia, Universidade Federal do Rio Grande do Norte, Natal, 2019.
Autor
Azevedo, Rebeca Gondim Cabral Medeiros de
Resumen
Brazil is considered one of the countries with the largest biodiversity on the planet, compressing around 20% of the world's plant species. Among the hundreds of existing genera, the Turnera genus has 141 cataloged species, with Turnera diffusa, Turnera subulata and Turnera ulmifolia being the most used in folk medicine. Extracts from these species are used to treat chronic, gastrointestinal, respiratory and genital diseases. Other traditional uses include its antimicrobial, antitussive, expectorant and diuretic activities. For this systematic review, the protocol was followed according to the PRISMA statement; the articles were searched in databases MEDLINE, Lilacs, Web of Science, Scielo, Science Direct and Pubmed. A total of 1.237 articles were found and of these, 53 were used to perform this systematic review. Regarding the chemical composition of the extracts, flavonoids, cyanogenic glycosides, alcohols, monoterpenes, sesquiterpenes, triterpenes, hydrocarbons, fatty acids, esters, ketones and aldehydes were isolated. The bioactivities studied for the genera Turnera include antioxidant, antibacterial, antiparasitic, antifungal, hypoglycemic, anti-inflammatory, anticoagulant, antitumor, anxiolytic, antidepressant, protective (gastro, hepato and neuroprotective) activities and aphrodisiac activities. In this review, current knowledge on ethnopharmacology, phytochemistry, therapeutic activities and toxicity of Turnera genus was compiled. Among the main activities reported, the aphrodisiac activity of Turnera diffusa and the potentiating effect of Turnera ulmifolia antibiotic activity against aminoglycoside resistant bacteria stand out.