masterThesis
Impacto da radiofrequência fracionada microablativa na saúde vaginal, microbiota e celularidade de mulheres pós-menopausadas
Fecha
2020-03-06Registro en:
SARMENTO, Ayane Cristine Alves. Impacto da radiofrequência fracionada microablativa na saúde vaginal, microbiota e celularidade de mulheres pós-menopausadas. 2020. 68f. Dissertação (Mestrado em Ciências da Saúde) - Centro de Ciências da Saúde, Universidade Federal do Rio Grande do Norte, Natal, 2020.
Autor
Sarmento, Ayane Cristine Alves
Resumen
The aim of study was to evaluate the effects of microablative fractional radiofrequency
(MAFRF) as a possible option in the non-hormonal treatment of symptoms from
menopause. We studied 55 healthy postmenopausal women before and after
treatment regarding vaginal health index (VHI), vaginal microbiota, vaginal pH, and cell
maturation. Three applications of MAFRF were performed in the vagina/vaginal
introitus. During the whole treatment, six vaginal smears were obtained and stained by
the Papanicolaou technique for determining the degree of maturation of the vaginal
epithelium, as well as stained according to the Gram procedure for classification of
vaginal flora, following the criteria of Spiegel. For vaginal pH determination, the pH
indicator strips were applied against the vaginal wall. Statistical analysis was
performed using SPSS for Windows (version 17.0). Data presented were reported as
mean ± standard deviation. Differences were analyzed using the statistical method of
generalized estimation equations with autoregressive correlation structure "1" and
robust standard errors. The mean age was 59.8 ± 4.2 years, and the time of
menopause was 15.4 ± 4.5 years. After treatment, there was an increase in the
percentage of lactobacilli (p<0.001). Consequently, there was a progressive decrease
in vaginal pH during the treatment (p<0.001). Regarding cell maturation, there was a
decrease in the percentage of parabasal cells (p=0.001) and an increase in the
percentage of superficial cells (p<0.001). Additionally, there was also improvement in
the VHI index. The mean values of the VHI before and after treatment were 13.2 ± 5.6
and 22.5 ± 3.7, respectively (p<0.001).