doctoralThesis
Efeitos da eletroestimulação transcraniana por corrente contínua sobre a dor, capacidade funcional submáxima e estado de humor em mulheres com dismenorreia primária
Fecha
2020-08-10Registro en:
VARELLA, Larissa Ramalho Dantas. Efeitos da eletroestimulação transcraniana por corrente contínua sobre a dor, capacidade funcional submáxima e estado de humor em mulheres com dismenorreia primária. 2020. 82f. Tese (Doutorado em Fisioterapia) - Centro de Ciências da Saúde, Universidade Federal do Rio Grande do Norte, Natal, 2020.
Autor
Varella, Larissa Ramalho Dantas
Resumen
Introduction: Primary dysmenorrhea (PD) is a chronic condition that negatively
affects women's lives in many social, emotional and physical aspects. So far, drug
therapy and thermotherapy have been the most effective means of treating
dysmenorrhea, but these have undesirable adverse reactions or short-term local
effects. Transcranial direct current electrical stimulation (tDCS) is a non-invasive
cortical stimulation technique that promotes changes in brain functioning, and seems
to have good effects on pain and functionality. To date, there are no studies of this
therapy on the dorsolateral prefrontal cortex (DLPFC) in patients with PD.
Objectives: The main objective is to investigate the effect of tDCS on the DLPFC on
pain in patients with PD. The secondary outcomes were functionality and mood.
Methods: A double blind randomized controlled clinical trial was carried out. 26
volunteers with PD were randomized into two groups. The tDCS group received
therapy for 5 consecutive days, while the Sham group performed the same protocol,
but the current was turned on for a period of 30 seconds and then turned off. tDCS
was performed in the DLPFC, with an intensity of 2mA. Participants in both groups
were assessed at two times: in the first 24 hours of the initial menstrual cycle (AV1),
in the first 24 hours of the next menstrual cycle and after intervention (AV2). To
evaluate the primary outcome, the numerical pain scale was used. For the secondary
outcomes mood (affectivity and anxiety), and of functionality, were used the Hamilton
anxiety rating scale, the positive and negative affect scale, and de six-minute walk
test, respectively. Results: No significant interaction between intervention and time
was found in the NRS [F (2.44) = 1.358, p = 0.26] and a significant effect of time was
noted [F (2.44) = 4.446, p = 0.01] was found. The active group showed a significant
reduction in anxiety (p = 0.03) with a mean difference of 5.12 (95% CI 0.79 to 11.05).
There were no significant differences between positive and negative affect (p = 0.95
and p = 0.15, respectively). Submaximal aerobic performance was significantly
higher in the active group [F (2.21) = 5.591, p = 0.02], with a mean difference of
70.87 (95% CI 8.53 to 133.21). Conclusion: tDCS in the DLPFC region appears in
this study as a resource with satisfactory effect on functionality. This is effective in
reducing anxiety, improving mood and functionality.