Translocation of 99mTc labelled bacteria after intestinal ischemia and reperfusion

dc.creatorJoão, Samir Assi
dc.creatorAlencar, Suelene Suassuna Silvestre de
dc.creatorMedeiros, Aldo da Cunha
dc.creatorDiniz, Simone Otília Fernandes
dc.creatorCardoso, Valbert Nascimento
dc.creatorBrandt, Carlos Teixeira
dc.date.accessioned2013-09-30T15:29:25Z
dc.date.accessioned2022-10-05T23:07:07Z
dc.date.available2013-09-30T15:29:25Z
dc.date.available2022-10-05T23:07:07Z
dc.date.created2013-09-30T15:29:25Z
dc.date.issued2004
dc.identifierJOÃO, Samir Assi ; ALENCAR ,Suelene Suassuna Silvestre de ; MEDEIROS, Aldo da Cunha ; DINIZ, Simone Otília Fernandes ; CARDOSO, Valbert Nascimento ; BRANDT, Carlos Teixeira. Translocation of 99mTc labelled bacteria after intestinal ischemia and reperfusion. Acta Cirúrgica Brasileira, São Paulo, v. 19, n.4, p. 328-333, 2004. Disponível em:<http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502004000400003> Acesso em: 30 set. 2013
dc.identifier1678-2674
dc.identifierhttps://repositorio.ufrn.br/jspui/handle/1/6291
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/3947273
dc.description.abstractIschemia and reperfusion of the small intestine disrupts gut barrier, causes bacterial translocation and activates inflammatory responses. An experimental study was planned to evaluate if 99mTc labelled Escherichia coli translocates to mesenteric lymph nodes, liver, spleen, lung and serum of rats submitted to mesenteric ischemia/reperfusion. Additionally, it was observed if the time of reperfusion influences the level of translocation. METHODS: Forty male Wistar rats underwent 45 minutes of gut ischemia by occlusion of the superior mesenteric artery. The translocation of labelled bacteria to different organs and portal serum was determined in rats reperfused for 30 minutes, 24 hours, sham(S) and controls(C), using radioactivity count and colony forming units/g (CFU). RESULTS: All the organs from rats observed for 24 hours after reperfusion had higher levels of radioactivity and positive cultures (CFU) than did the organs of rats reperfused for 30 minutes, C and S, except in the spleen (p<0,01). CONCLUSION: The results of this study indicated that intestinal ischemia/reperfusion led to bacterial translocation, mostly after 24 hours of reperfusion
dc.languageeng
dc.rightsAcesso Aberto
dc.subjectBacterial translocation
dc.subjectIschemia
dc.subjectReperfusion
dc.subjectIntestine
dc.subject99mTechnecium labelled bacteria
dc.titleTranslocation of 99mTc labelled bacteria after intestinal ischemia and reperfusion
dc.typearticle


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