masterThesis
Organização nuclear do sistema serotonérgico no encéfalo de morcegos Artibeus planirostris
Fecha
2015-07-09Registro en:
LEITE, Mariana Dias. Organização nuclear do sistema serotonérgico no encéfalo de morcegos Artibeus planirostris. 2015. 76f. Dissertação (Mestrado em Psicobiologia) - Centro de Biociências, Universidade Federal do Rio Grande do Norte, Natal, 2015.
Autor
Leite, Mariana Dias
Resumen
Serotonin or 5-hydroxytryptamine (5-HT) is a substance found in many tissues of the
body, including the nervous system acting as a neurotransmitter. Within the neuro-axis,
the location of the majority of the 5-HT neurons is superimposed with raphe nuclei of the
brain stem, in the median line or its vicinity, so that neuronal 5-HT can be considered a
marker of the raphe nuclei. Serotonergic neurons are projected to almost all areas of the
brain. Studies show the participation of serotonin in regulating the temperature, feeding
behavior, sexual behavior, biological rhythms, sleep, locomotor function, learning,
among others. The anatomy of these groups has been revised in many species,
including mouse, rabbit, cat and primates, but never before in a bat species from South
America. This study aimed to characterize the serotonergic clusters in the brain of the
bat Artibeus planirostris through immunohistochemistry for serotonin. Seven adult bat
males of Artibeus planirostris species (Microchiroptera, Mammalia) were used in this
study. The animals were anesthetized, transcardially perfused and their brains were
removed. Coronal sections of the frozen brain of bats were obtained in sliding microtome
and subjected to immunohistochemistry for 5-HT. Delimit the caudal linear (CLi), dorsal
(DR), median (MnR), paramedian (PMnR), pontine (PNR), magnus (MgR), pallidus
(RPA) and obscurus (ROb) raphe nucleus, in addition to the groups B9 and rostral and
caudal ventrolateral (RVL/CVL). The serotonergic groups of this kind of cheiroptera
present morphology and cytoarchitecture relatively similar to that described in rodents
and primates, confirming the phylogenetic stability of these cell clusters.