dc.creator | Rêgo, Amália Cínthia Meneses do | |
dc.creator | Araújo Filho, Irami | |
dc.creator | Azevedo, Ítalo Medeiros | |
dc.creator | Jácome, Daniel Tôrres | |
dc.creator | Ramalho, Rachel de Alcântara Oliveira | |
dc.creator | Medeiros, Aldo Cunha | |
dc.date.accessioned | 2013-09-30T15:07:41Z | |
dc.date.accessioned | 2022-10-05T23:01:45Z | |
dc.date.available | 2013-09-30T15:07:41Z | |
dc.date.available | 2022-10-05T23:01:45Z | |
dc.date.created | 2013-09-30T15:07:41Z | |
dc.date.issued | 2010 | |
dc.identifier | RÊGO, Amália Cínthia Meneses do ; ARAÚJO FILHO, Irami ; AZEVEDO, Ítalo Medeiros ; JÁCOME, Daniel Tôrres ; RAMALHO, Rachel de Alcântara Oliveira ; MEDEIROS, Aldo Cunha. Biodistribution of technetium-99m pertechnetate after Roux-en-Y gastric bypass (Capella technique) in rats. Acta Cirurgica Brasileira, v. 25, p. 9-12, 2010. Disponível em:<http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502010000100004> Acesso em: 25 set. 2013. | |
dc.identifier | 1678-2674 | |
dc.identifier | https://repositorio.ufrn.br/jspui/handle/1/6287 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/3944855 | |
dc.description.abstract | The biodistribution of sodium pertechnetate, the most used radiopharmaceutical in nuclear medicine, has not been studied in
details after bariatric surgery. The objective was to investigate the effect of Roux-en-Y gastric bypass (RYGB) on biodistribution of
sodium pertechnetate (Na99mTc-) in organs and tissues of rats. Methods: Twelve rats were randomly divided into two groups of 6 animals
each. The RYGB group rats were submitted to the Roux-en-Y gastric bypass and the control group rats were not operated. After 15 days,
all rats were injected with 0.1mL of Na99mTc- via orbital plexus with average radioactivity of 0.66 MBq. After 30 minutes, liver, stomach,
thyroid, heart, lung, kidney and femur samples were harvested, weighed and percentage of radioactivity per gram (%ATI/g) of each
organ was determined by gama counter Wizard Perkin-Elmer. We applied the Student t test for statistical analysis, considering p<0.05 as
significant. Results: Significant reduction in mean %ATI/g was observed in the liver, stomach and femur in the RYGB group animals,
compared with the control group rats (p<0.05). In other organs no significant difference in %ATI/g was observed between the two
groups. Conclusion: This work contributes to the knowledge that the bariatric surgery RYGB modifies the pattern of biodistribution of
Na99mTc | |
dc.language | eng | |
dc.rights | Acesso Aberto | |
dc.subject | Biological Availability | |
dc.subject | Bariatric Surgery | |
dc.subject | Sodium Pertechnetate Tc 99m | |
dc.subject | Radiopharmaceuticals | |
dc.subject | Rats | |
dc.title | Biodistribution of technetium-99m pertechnetate after Roux-en-Y gastric bypass (Capella technique) in rats | |
dc.type | article | |