Artigo
Biocompatibility and biomineralization assessment of a new root canal sealer and root-end filling material
Fecha
2013-04-01Registro en:
Dental Traumatology, v. 29, n. 2, p. 145-150, 2013.
1600-4469
1600-9657
10.1111/j.1600-9657.2012.01142.x
WOS:000315743900012
2-s2.0-84874726202
9235743081667362
8813777272581972
Autor
Universidade Estadual Paulista (Unesp)
Resumen
Objective: This study investigated the short-term subcutaneous tissue reaction and biomineralization ability of two epoxy-based root canal sealers containing calcium hydroxide (MBP and MBPc) and ProRoot MTA. Materials and methods: Polyethylene tubes containing the materials were implanted into the dorsal connective tissue of Wistar rats (n = 52) for 7 or 30 days; empty implanted tubes served as controls. Specimens were stained with hematoxylin-eosin and von Kossa stain or left unstained for observation under polarized light. Qualitative and quantitative evaluations of all tissue reactions were performed. One-way anova and the Kruskal-Wallis test were used for statistical analysis (P < 0.05). Results: No significant differences were observed among the groups. All three materials induced mild-to-moderate tissue reactions at 7 days, which decreased over time. Dystrophic mineralization and birefringent structures were observed only in the ProRoot MTA ® group. Conclusion: Both MBP and MBPc appear to be biocompatible but do not stimulate biomineralization. © 2012 John Wiley & Sons A/S.