Artigo
Toward pH-controllable bioelectrocatalysis for hydrogen peroxide based on polymer brushes
Fecha
2013-04-01Registro en:
Electrochemistry Communications, v. 29, p. 41-44.
1388-2481
10.1016/j.elecom.2012.12.026
WOS:000316531700011
2-s2.0-84873434066
7781282422851911
Autor
Universidade Estadual Paulista (Unesp)
Universidade Estadual de Campinas (UNICAMP)
Universidade de São Paulo (USP)
Resumen
In the present work, a biosensor was built with smart material based on polymer brushes. The biosensor demonstrated a pH-sensitive on-off property, and it was further used to control or modulate the electrochemical responses of the biosensor. This property could be used to realize pH-controlled electrochemical reaction of hydrogen peroxide and HRP immobilized on polymer brushes. The composite film also showed excellent amperometric i-t response toward hydrogen peroxide in the concentration range of 0-13 μM. In future, this platform might be used for self-regulating targeted diagnostic, drug delivery and biofuel cell based on controllable bioelectrocatalysis. © 2013 Elsevier B.V.