Treatment of experimental periodontitis in rats using repeated adjunctive antimicrobial photodynamic therapy

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorUniversity Center of the Educational Foundation of Barretos (UNIFEB)
dc.contributorFederal University of Alfenas
dc.date.accessioned2014-05-27T11:27:27Z
dc.date.accessioned2022-10-05T18:40:20Z
dc.date.available2014-05-27T11:27:27Z
dc.date.available2022-10-05T18:40:20Z
dc.date.created2014-05-27T11:27:27Z
dc.date.issued2013-01-01
dc.identifierLasers in Medical Science, v. 28, n. 1, p. 143-150, 2013.
dc.identifier0268-8921
dc.identifier1435-604X
dc.identifierhttp://hdl.handle.net/11449/74125
dc.identifier10.1007/s10103-012-1099-y
dc.identifierWOS:000313096400021
dc.identifier2-s2.0-84872314410
dc.identifier4068921369233125
dc.identifier9831236034935598
dc.identifier8399870097572073
dc.identifier4774447118127346
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/3923089
dc.description.abstractThe aim of this study was to histologically and histometrically evaluate the influence of repeated adjunctive antimicrobial photodynamic therapy (aPDT) on bone loss (BL) in furcation areas in rats. Periodontitis was induced by placing a ligature around the mandibular molar in 75 rats. The animals were divided into five groups: the SS group was treated with saline solution (SS); the SRP group received scaling and root planing (SRP); the aPDT1 group received SRP as well as toluidine blue (TBO) and low-level laser therapy (LLLT; InGaAlP, 660 nm; 4.94 J/cm2/point) postoperatively at 0 h; the aPDT2 group received SRP as well as TBO and LLLT postoperatively at 0, 24, 28, and 72 h; and the aPDT3 group received SRP, TBO, and LLLT postoperatively at 0, 48, 96, and 144 h. The area of BL in the furcation region of the molar was histometrically analyzed. Data were analyzed statistically (P < 0.05). Animals treated with a single episode of aPDT showed less BL at days 7 and 30 than those who received only SRP treatment. No significant differences were found among the aPDT groups (P > 0.05). Repeated aPDT did not improve BL reduction when compared to a single episode of aPDT. © 2012 Springer-Verlag London Ltd.
dc.languageeng
dc.relationLasers in Medical Science
dc.relation1.949
dc.relation0,713
dc.rightsAcesso restrito
dc.sourceScopus
dc.subjectAlveolar bone loss
dc.subjectLasers
dc.subjectPeriodontitis
dc.subjectPhotochemotherapy
dc.subjecttolonium chloride
dc.subjectanimal experiment
dc.subjectanimal model
dc.subjectanimal tissue
dc.subjectcontrolled study
dc.subjecthistology
dc.subjecthistometry
dc.subjectindium gallium aluminum phosphorus laser
dc.subjectlaser
dc.subjectlow level laser therapy
dc.subjectmale
dc.subjectmolar tooth
dc.subjectnonhuman
dc.subjectosteolysis
dc.subjectperiodontitis
dc.subjectphotodynamic therapy
dc.subjectpreventive dentistry
dc.subjectpriority journal
dc.subjectrat
dc.subjectAlveolar Bone Loss
dc.subjectAnalysis of Variance
dc.subjectAnimals
dc.subjectDental Scaling
dc.subjectLaser Therapy, Low-Level
dc.subjectMale
dc.subjectRats
dc.subjectRats, Wistar
dc.subjectRoot Planing
dc.subjectSodium Chloride
dc.subjectTolonium Chloride
dc.titleTreatment of experimental periodontitis in rats using repeated adjunctive antimicrobial photodynamic therapy
dc.typeArtigo


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