Autoradiographic investigation of effects of high-dose colchicine on dentinogenesis in rat incisors

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T04:00:44Z
dc.date.accessioned2022-10-05T17:24:10Z
dc.date.available2014-05-27T04:00:44Z
dc.date.available2022-10-05T17:24:10Z
dc.date.created2014-05-27T04:00:44Z
dc.date.issued1988-01-01
dc.identifierActa Anatomica, v. 133, n. 1, p. 45-49, 1988.
dc.identifier0001-5180
dc.identifierhttp://hdl.handle.net/11449/63837
dc.identifier10.1159/000146613
dc.identifier2-s2.0-0023754172
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/3914009
dc.description.abstractTwelve female Wistar rats received 1.5 mg/kg of colchicine (CLC) intravenously. Control animals were similarly injected with isotonic saline solution. The animals were killed 5 h, 24 h, 3 days and 7 days after injection. Ninety minutes prior to sacrifice, all animals received an intraperitoneal injection of 3H-proline. Autoradiograms of maxillary incisors showed that CLC increased the retention of the labeled precursor in the odontoblasts. It was also shown that the odontoblasts in the different sectors of the rat incisor present different sensitivities to the CLC action.
dc.languageeng
dc.relationActa Anatomica
dc.rightsAcesso restrito
dc.sourceScopus
dc.subjectcolchicine
dc.subjectradioisotope
dc.subjectanimal cell
dc.subjectanimal experiment
dc.subjectdentin
dc.subjectincisor
dc.subjectintravenous drug administration
dc.subjectnonhuman
dc.subjectodontoblast
dc.subjectrat
dc.subjecttooth development
dc.subjectAnimal
dc.subjectAutoradiography
dc.subjectColchicine
dc.subjectDentin
dc.subjectDentinogenesis
dc.subjectFemale
dc.subjectIncisor
dc.subjectProline
dc.subjectRats
dc.subjectRats, Inbred Strains
dc.titleAutoradiographic investigation of effects of high-dose colchicine on dentinogenesis in rat incisors
dc.typeArtigo


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