dc.contributor | Universidade Estadual Paulista (Unesp) | |
dc.date.accessioned | 2014-05-20T15:25:10Z | |
dc.date.accessioned | 2022-10-05T16:31:58Z | |
dc.date.available | 2014-05-20T15:25:10Z | |
dc.date.available | 2022-10-05T16:31:58Z | |
dc.date.created | 2014-05-20T15:25:10Z | |
dc.date.issued | 1997-08-01 | |
dc.identifier | Physiology & Behavior. Oxford: Pergamon-Elsevier B.V., v. 62, n. 2, p. 311-316, 1997. | |
dc.identifier | 0031-9384 | |
dc.identifier | http://hdl.handle.net/11449/35627 | |
dc.identifier | 10.1016/S0031-9384(97)88986-X | |
dc.identifier | WOS:A1997XN41000013 | |
dc.identifier | 1023597870118105 | |
dc.identifier | 6551236936295697 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/3907525 | |
dc.description.abstract | In this study, we investigated the participation of adrenergic receptors of the median preoptic area (MnPO) and the participation of ventromedial hypothalamus (VMH) in angiotensin II- (ANG II)-induced water intake and presser responses. Male rats with sham or electrolytic VMH lesions and a stainless steel cannula implanted into the MnPO were used. Noradrenaline, clonidine (an alpha(2)-adrenergic receptor agonist), or phenylephrine (an alpha(1)-adrenergic receptor agonist) injected into the MnPO of sham-lesioned rats reduced water ingestion induced by ANG II injected into the same area. In VMH-lesioned rats ANG II-induced water intake increased with a previous injection of noradrenaline, phenylephrine, or isoproterenol. The presser response induced by ANG II injected into the MnPO was reduced in VMH-lesioned rats, whereas the presser response induced by clonidine was abolished. Previous treatment with noradrenaline and phenylephrine into the MnPO of sham-lesioned rats produced a presser response, and a hypotensive response was obtained with the previous administration of noradrenaline, phenylephrine or isoproterenol into the MnPO of VMH-lesioned rats. These results show that VMH is essential for the dipsogenic and presser responses induced by adrenergic and angiotensinergic activation of the MnPO in rats. (C) 1997 Elsevier B.V. | |
dc.language | eng | |
dc.publisher | Elsevier B.V. | |
dc.relation | Physiology & Behavior | |
dc.relation | 2.517 | |
dc.relation | 1,088 | |
dc.rights | Acesso restrito | |
dc.source | Web of Science | |
dc.subject | water intake | |
dc.subject | arterial pressure | |
dc.subject | ANG II | |
dc.subject | adrenergic agonists | |
dc.subject | MnPO | |
dc.subject | VMH | |
dc.title | Ventromedial hypothalamus lesions increase the dipsogenic responses and reduce the pressor responses to median preoptic area activation | |
dc.type | Artigo | |