Artigo
Immunohistochemical study of acinic cell carcinoma of minor salivary gland
Date
1997-05-01Registration in:
Oral Oncology. Oxford: Pergamon-Elsevier B.V., v. 33, n. 3, p. 204-208, 1997.
0964-1955
10.1016/S0964-1955(96)00064-4
WOS:A1997XN20200009
9544257482512671
Author
Universidade Estadual Paulista (Unesp)
Universidade de São Paulo (USP)
Abstract
Acinic cell carcinoma (ACC) is a rare salivary gland tumour, making up 4% of all minor salivary gland tumours. Typically, it is composed of acinic cells although transitional and duct-like cells are also identified. In the present study, a panel of antibodies was applied to eight minor salivary gland ACCs. Antibodies tested were: cytokeratins 7, 8, 13, 14, 18, 19, vimentin and actin (HHF35). Immunohistochemical staining revealed that cytokeratin 8, among the tested antibodies, was the more specific to neoplastic cells with a pattern of distribution quite variable and peculiar. This staining may be useful in the recognition of neoplastic acinic cells. (C) 1997 Elsevier B.V. Ltd.