dc.contributorInst Nacl Tecnol Agropecuaria
dc.contributorEmpresa Brasileira de Pesquisa Agropecuária (EMBRAPA)
dc.contributorINTA EEA Bariloche
dc.contributorUniv Buenos Aires
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2013-09-30T18:25:14Z
dc.date.accessioned2014-05-20T13:42:36Z
dc.date.accessioned2022-10-05T14:03:41Z
dc.date.available2013-09-30T18:25:14Z
dc.date.available2014-05-20T13:42:36Z
dc.date.available2022-10-05T14:03:41Z
dc.date.created2013-09-30T18:25:14Z
dc.date.created2014-05-20T13:42:36Z
dc.date.issued2008-09-15
dc.identifierVeterinary Immunology and Immunopathology. Amsterdam: Elsevier B.V., v. 125, n. 1-2, p. 198-202, 2008.
dc.identifier0165-2427
dc.identifierhttp://hdl.handle.net/11449/14817
dc.identifier10.1016/j.vetimm.2008.04.015
dc.identifierWOS:000259313300020
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/3890136
dc.description.abstractClostridium perfringens type D-producing epsilon toxin is a common cause of death in sheep and goats worldwide. Although anti-epsilon toxin serum antibodies have been detected in healthy non-vaccinated sheep, the information regarding naturally acquired antibodies in ruminants is scanty. The objective of the present report was to characterize the development of naturally acquired antibodies against C. perfringens epsilon toxin in goats. The levels of anti-epsilon toxin antibodies in blood serum of goat kids from two different herds were examined continuously for 14 months. Goats were not vaccinated against any clostridial disease and received heterologous colostrums from cows that were not vaccinated against any clostridial disease. During the survey one of these flocks suffered an unexpectedly severe C. perfringens type D enterotoxemia outbreak. The results showed that natural acquired antibodies against C. perfringens epsilon toxin can appear as early as 6 weeks in young goats and increase with the age without evidence of clinical disease. The enterotoxemia outbreak was coincident with a significant increase in the level of anti-epsilon toxin antibodies. (C) 2008 Elsevier B.V. All rights reserved.
dc.languageeng
dc.publisherElsevier B.V.
dc.relationVeterinary Immunology and Immunopathology
dc.relation1.632
dc.relation0,680
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectClostridium perfringens
dc.subjectepsilon toxin
dc.subjectimmune response
dc.subjectCaprine
dc.titleNaturally acquired antibodies against Clostridium perfringens epsilon toxin in goats
dc.typeArtigo


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