Spectrophotometric determination of sparfloxacin in pharmaceutical formulations using bromothymol blue

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorUniversidade Federal do Rio Grande do Sul (UFRGS)
dc.date.accessioned2014-05-20T13:24:38Z
dc.date.accessioned2022-10-05T13:14:26Z
dc.date.available2014-05-20T13:24:38Z
dc.date.available2022-10-05T13:14:26Z
dc.date.created2014-05-20T13:24:38Z
dc.date.issued2001-10-01
dc.identifierJournal of Pharmaceutical and Biomedical Analysis. Oxford: Pergamon-Elsevier B.V., v. 26, n. 3, p. 501-504, 2001.
dc.identifier0731-7085
dc.identifierhttp://hdl.handle.net/11449/7703
dc.identifier10.1016/S0731-7085(01)00429-0
dc.identifierWOS:000172055000017
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/3884514
dc.description.abstractA visible light spectrophotometric method is described for them determination of sparfloxacin in tablets. The procedure is based on the complexation of bromothymol blue 0.5% and sparfloxacin to form a compound of yellow colour with maximum absorption at 385 nm. The Lambert-Beer law was obeyed in the concentration range of 2-12 mg/l. The present study describes a sensitive and accurate method for the determination of the concentration of sparfloxacin in tablets. It was also found that the excipients in the commercial tablet preparation did not interfere with the assay.
dc.languageeng
dc.publisherElsevier B.V.
dc.relationJournal of Pharmaceutical and Biomedical Analysis
dc.relation2.831
dc.relation0,919
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectfluoroquinolone
dc.subjectpharmaceutical analysis
dc.subjectsparfloxacin
dc.subjectvisible light spectrophotometry
dc.titleSpectrophotometric determination of sparfloxacin in pharmaceutical formulations using bromothymol blue
dc.typeArtigo


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