dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:22:03Z
dc.date.accessioned2022-10-05T13:06:11Z
dc.date.available2014-05-20T13:22:03Z
dc.date.available2022-10-05T13:06:11Z
dc.date.created2014-05-20T13:22:03Z
dc.date.issued2005-07-01
dc.identifierContraception. New York: Elsevier B.V., v. 72, n. 1, p. 77-80, 2005.
dc.identifier0010-7824
dc.identifierhttp://hdl.handle.net/11449/6430
dc.identifier10.1016/j.contraception.2005.02.001
dc.identifierWOS:000230425200014
dc.identifier4165274708509804
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/3883560
dc.description.abstractThis study aimed to analyze the effects of nandrolone decanoate on the ovaries and uterus of adult females rats. This drug was administered intraperitoneally, at one, two and three doses of 3 mg nandrolone decanoate/kg of body weight, respectively, in the first, second and third week of treatment. The females of the control group received a physiological solution. The rats treated with nandrolone decanoate showed estral acyclicity and there was destruction of follicular units and an absence of corpus luteum in the ovaries. In the uterus, the drug promoted morphological alterations, characterized by vacuolated epithelium and endometrial stroma fibrosis. Ovary, uterus and pituitary weights were not affected by the steroid treatment. Nandrolone decanoate affects the sexual cycle and promotes histological alterations in the ovaries and uterus of adult female rats. (C) 2005 Elsevier B.V. All rights reserved.
dc.languageeng
dc.publisherElsevier B.V.
dc.relationContraception
dc.relation2.894
dc.relation1,921
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectnandrolone decanoate
dc.subjectovaries
dc.subjectuterus
dc.subjecthistology
dc.subjectadult female rats
dc.titleHistological assessment of ovaries and uterus of rats subjected to nandrolone decanoate treatment
dc.typeArtigo


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