dc.contributor | Universidade Estadual Paulista (Unesp) | |
dc.contributor | Universidade Estadual do Norte Fluminense | |
dc.date.accessioned | 2014-05-20T13:17:34Z | |
dc.date.accessioned | 2022-10-05T12:46:56Z | |
dc.date.available | 2014-05-20T13:17:34Z | |
dc.date.available | 2022-10-05T12:46:56Z | |
dc.date.created | 2014-05-20T13:17:34Z | |
dc.date.issued | 2008-12-01 | |
dc.identifier | Brazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 12, n. 6, p. 469-471, 2008. | |
dc.identifier | 1413-8670 | |
dc.identifier | http://hdl.handle.net/11449/3994 | |
dc.identifier | 10.1590/S1413-86702008000600004 | |
dc.identifier | S1413-86702008000600004 | |
dc.identifier | WOS:000264200300004 | |
dc.identifier | S1413-86702008000600004.pdf | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/3881678 | |
dc.description.abstract | The obtainment of transgenic edible plants carrying recombinant antigens is a desired issue in search for economic alternatives viewing vaccine production. Here we report a strategy for genetic transformation of lettuce plants (Lactuca sativa L.) using the surface antigen HBsAg of hepatitis B virus. Transgenic lettuce seedlings were obtained through the application of a regulated balance of plant growth regulators. Genetic transformation process was acquired by cocultivation of cotyledons with Agrobacterium tumefaciens harboring the recombinant plasmid. It is the first description of a lettuce Brazilian variety Vitória de Verão genetically modified. | |
dc.language | eng | |
dc.publisher | Brazilian Society of Infectious Diseases | |
dc.relation | Brazilian Journal of Infectious Diseases | |
dc.relation | 2.083 | |
dc.relation | 0,817 | |
dc.rights | Acesso aberto | |
dc.source | SciELO | |
dc.subject | Edible vaccine | |
dc.subject | Hepatitis B | |
dc.subject | Oral immunization | |
dc.subject | Recombinant antigen | |
dc.subject | Transgenic plants | |
dc.title | Transgenic lettuce seedlings carrying hepatitis B virus antigen HBsAg | |
dc.type | Artigo | |