| dc.creator | Siqueira, Lucas | |
| dc.creator | Venske, Sandra | |
| dc.date | 2021-08-29 | |
| dc.date.accessioned | 2022-10-04T22:28:03Z | |
| dc.date.available | 2022-10-04T22:28:03Z | |
| dc.identifier | https://seer.ufrgs.br/index.php/rita/article/view/Vol28_Nr2_11 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/3870454 | |
| dc.description | Protein Structure Prediction (PSP) problem is to determine the three-dimensional structure of a protein only from its primary structure. Misfolding of a protein causes human diseases. Thus, the knowledge of the structure and functionality of proteins, combined with the prediction of their structure is a complex problem and a challenge for the area of computational biology. The metaheuristic optimization algorithms are naturally applicable to support in solving NP-hard problems.These algorithms are bio-inspired, since they were designed based on procedures found in nature, such as the successful evolutionary behavior of natural systems. In this paper, we present a survey on methods to approach the \textit{ab initio} protein structure prediction based on evolutionary computing algorithms, considering both single and multi-objective optimization. An overview of the works is presented, with some details about which characteristics of the problem are considered, as well as specific points of the algorithms used. A comparison between the approaches is presented and some directions of the research field are pointed out. | en-US |
| dc.format | application/pdf | |
| dc.language | eng | |
| dc.publisher | Instituto de Informática - Universidade Federal do Rio Grande do Sul | en-US |
| dc.relation | https://seer.ufrgs.br/index.php/rita/article/view/Vol28_Nr2_11/pdf | |
| dc.rights | Copyright (c) 2021 Lucas Siqueira, Sandra Venske | pt-BR |
| dc.source | Revista de Informática Teórica e Aplicada; Vol. 28 No. 2 (2021); 11-24 | en-US |
| dc.source | Revista de Informática Teórica e Aplicada; v. 28 n. 2 (2021); 11-24 | pt-BR |
| dc.source | 2175-2745 | |
| dc.source | 0103-4308 | |
| dc.subject | Protein Structure Prediction | en-US |
| dc.subject | Evolutionary Algorithms | en-US |
| dc.subject | Ab Initio | en-US |
| dc.subject | Bioinformatics | en-US |
| dc.title | Ab Initio Protein Structure Prediction Using Evolutionary Approach: A Survey | en-US |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:eu-repo/semantics/publishedVersion | |
