Produção de antiveneno botrópico em ovos de galinha

dc.contributorZelia Ines Portela Lobato
dc.contributorDavid Toledo Velarde
dc.contributorNelson Rodrigo da Silva Martins
dc.creatorAmanda Soriano Araujo de Souza Moreira
dc.date.accessioned2019-08-13T04:32:00Z
dc.date.accessioned2022-10-03T22:16:47Z
dc.date.available2019-08-13T04:32:00Z
dc.date.available2022-10-03T22:16:47Z
dc.date.created2019-08-13T04:32:00Z
dc.date.issued2007-12-14
dc.identifierhttp://hdl.handle.net/1843/SSLA-7UCJ8X
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/3797982
dc.description.abstractThe aim of this work was develop an antivenom from eggs of hens immunized with Bothrops antigen and to evaluate its potency. Adults Single Comb White Leghorn hens were immunized with venom of five species of snakes of the genus Bothrops. The purification of the immunoglobulin Y (IgY) was done by ammonium sulfate 20% precipitation (w/v) and 2.69mg of pure IgY/ml of yolk was produced. The IgY from egg-yolk neutralized the toxic lethal activities of Bothrops venom. The median effective dose (ED-50) of the IgY anti-Bothrops venom was365ìL/2LD-50 and 1ml neutralized 0.154mg of venom
dc.publisherUniversidade Federal de Minas Gerais
dc.publisherUFMG
dc.rightsAcesso Aberto
dc.subjectBothrops
dc.subjectSoro antiofídico
dc.subjectIgY
dc.subjectGallus gallus domesticus
dc.titleProdução de antiveneno botrópico em ovos de galinha
dc.typeDissertação de Mestrado


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