dc.creator | Galvis, Fabian | |
dc.creator | Moreno Rozo, laura Yolima | |
dc.date.accessioned | 2021-12-09T20:41:04Z | |
dc.date.accessioned | 2022-09-28T18:31:47Z | |
dc.date.available | 2021-12-09T20:41:04Z | |
dc.date.available | 2022-09-28T18:31:47Z | |
dc.date.created | 2021-12-09T20:41:04Z | |
dc.date.issued | 2019-06 | |
dc.identifier | http://repositorio.ufps.edu.co/handle/ufps/1781 | |
dc.identifier | http://dx.doi.org/10.4067/S0716-10182019000300304 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/3704328 | |
dc.description.abstract | Background: The expression of CTX-M β-lactamases belonging to groups 1 and 9 in Klebsiella pneumoniae
produces high levels of resistance to ceftazidime, and they have a wide distribution worldwide. Aim: To identify
and characterize the blaCTX-M-Group1 and blaCTX-M-Group9 genes in K. pneumoniae isolates resistant to ceftazidime
in a hospital in San José de Cúcuta, Colombia. Material and Methods: Primers were designed for the identification
of K. pneumoniae and blaCTX-M genes by PCR. Subsequently, the genetic relationship of these isolates was analyzed
by REP-PCR. Results: A 38% of the 24 isolates identified by PCR as K. pneumoniae showed blaCTX-M-3. blaCTX-M-15
y blaCTX-M-32 genes (Group CTX-M-1) and 42% blaCTX-M14. blaCTX-M-24 y blaCTX-M-27 genes (Group CTX-M-9). The
phylogenetic analysis grouped the K. pneumoniae isolates into 4 clusters, showing correlation in clusters I, II
and IV, when comparing the genetic profiles with the type of sample and group of genes. Discussion: We found
a similar frequency of blaCTX-M-Group 1 and blaCTX-M-Group 9 genes in isolates of K. pneumoniae resistant to
ceftazidime. The correlation between the REP-PCR with the CTX-M groups and the type of sample revealed the
presence of three clonal pattern | |
dc.language | eng | |
dc.publisher | Revista Chilena de Infectologia | |
dc.publisher | Santiago de Chile , Chile | |
dc.relation | Revista chilena de infectología | |
dc.relation | Vol.36 No.3.(2019) | |
dc.relation | 311 | |
dc.relation | 3 (2019) | |
dc.relation | 304 | |
dc.relation | 36 | |
dc.relation | Galvis, F., & Moreno, L. (2019). Caracterización molecular y detección de genes blaCTX-M grupos 1 y 9 en Klebsiella pneumoniae resistentes a ceftazidima, en un hospital de San José de Cúcuta, Colombia. Revista chilena de infectología, 36(3), 304-311. | |
dc.relation | Molecular characterization and detection of genes blaCTX-M groups 1 and 9 in Klebsiella pneumoniae resistant to ceftazidime, in a hospital in San José de Cúcuta, Colombia | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.rights | Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) | |
dc.rights | This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited | |
dc.source | https://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-10182019000300304&lng=en&nrm=iso&tlng=en | |
dc.title | Caracterización molecular y detección de genes blaCTX-M grupos 1 y 9 en Klebsiella pneumoniae resistentes a ceftazidima, en un hospital de San José de Cúcuta, Colombia | |
dc.type | Artículos de revistas | |