dc.contributorIglesias Acosta, Jesús
dc.creatorAshton Izquierdo, Jorge Mario
dc.creatorQuiroz Rodríguez, Damián Arnoldo
dc.date.accessioned2017-07-25T20:30:12Z
dc.date.available2017-07-25T20:30:12Z
dc.date.created2017-07-25T20:30:12Z
dc.identifierhttps://hdl.handle.net/10901/10225
dc.identifierinstname:Universidad Libre
dc.identifierreponame:Repositorio Institucional Universidad Libre
dc.description.abstractEn el espectro de patológica aortica, enfermedad aneurismática es una entidad que se encuentra dentro de las primeras 20 causas de muerte en adultos en estados unidos, pero la historia natural de la enfermedad constituye un verdadero reto diagnóstico y terapéutico, por cuanto una gran parte de la enfermedad es silente y en gran medida asintomática, y su curso natural sin tratamiento se asocia a mortalidad extremadamente alta. Los aneurismas de la aorta torácica corresponden a una dilatación patológica de la pared del vaso como resultado de una debilidad en el tejido que la conforma. En este proceso intervienen diversos factores tanto inflamatorios, metabólicos, genéticos y físicos. Es la interacción de todos estos factores lo que determina el curso de la enfermedad; pero pese a los diversos frentes que juegan en la fisiopatología las repercusiones sistémicas clínicamente evidentes son pocas por lo que la progresión de la enfermedad suele ser con escasas a nulas manifestaciones clínicas y en muchos casos el debut de la patología suele ser suponer un gran riesgo para la vida del paciente. Es por esto que el desarrollo de técnicas de imágenes ha abierto un nuevo universo de conocimiento de la enfermedad, permitiendo conocer los cambios fisiopatológicos y documentar la progresión de esta; este punto permitió documentar con detalle la anatomía de las lesiones y su estrecha relación con las estructuras vecinas permitiendo la planeación quirúrgica; El detalle logrado con la evolución de las técnicas de imágenes permitieron el desarrollo de alternativas terapéuticas y con este el éxito terapéutico. Históricamente el abordaje terapéutico supuso una morbimortalidad elevada por cuanto existían limitaciones técnicas para los reparos abiertos y el golpe hemodinámico era tal que limito enormemente el resultado quirúrgico. Esto llevo a una gran búsqueda de alternativas para el manejo que derivaron en una revolución que buscaba mejorar el resultado. Esto se logró con el desarrollo técnico endovascular que ofrecieron una alternativa con mejores resultados. En la actualidad el manejo endovascular es la punta de lanza para el manejo de los aneurismas de la aorta toracoabdominal. Con estas técnicas se ha logrado mejorar sustancialmente los resultados en morbimortalidad y se amplió el espectro de lesiones tratables, ofreciendo a los pacientes una variedad de alternativas. Las técnicamente mínimamente invasivas rompieron con paradigmas que rodeaban el manejo de la patología aneurismática, con ayuda de los progresos en estudios imagenlógicos la caracterización de las lesiones se detalló aún más y permitió el conocimiento a fondo de la historia natural de la enfermedad permitiendo así elaborar estrategias de manejo. El desarrollo de toda una industria detrás de materiales y dispositivos permitió también que los avances se consolidaran hasta ocupar el nivel de importancia que hoy vemos. Es por eso que hoy en día los reparos endovasculares de aneurismas de aorta toracoabdominal confieren tasas de éxito por cuanto el impacto fisiológico de las intervenciones se disminuyó de manera abismal, lo que se ven reflejado en un margen de seguridad razonable para el paciente, la disminución sustancial de la morbimortalidad, la ampliación del espectro tratable de la enfermedad.
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dc.rightshttp://creativecommons.org/licenses/by-nc-nd/2.5/co/
dc.rightsAtribución-NoComercial-SinDerivadas 2.5 Colombia
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.subjectAneurismas
dc.subjectAorta torácica
dc.subjectMedicina
dc.titleAneurisma de aorta torácica


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