Generación de Nuevo Conocimiento: Artículos publicados en revistas especializadas - Electrónicos
Effects of exercise on carotid arterial wall thickness in obese pediatric populations: a meta-analysis of randomized controlled trials
Fecha
2017-04-01Autor
García-Hermoso, Antonio
González-Ruiz, Katherine
Triana-Reina, Hector Reynaldo
Olloquequi, Jordi
Ramírez-Vélez, Robinson
Institución
Resumen
Background: In pediatric populations, the use of carotid intima-media thickness (IMT) as a marker of cardiovascular risk has
increased. However, previous studies examining the effects of exercise training on arterial structure and function in obese children
and adolescents have shown inconsistent findings. The primary aim of this systematic review and meta-analysis is to expand on the
current body of literature by providing a quantitative estimate of the change in carotid IMT following exercise training as well as to
provide an exploratory analysis of potential moderators associated with the variation in response to an exercise training intervention
in overweight and obese youth.
Materials and Methods: A computerized search was made using three databases. The analysis was restricted to studies that
examined the effect of exercise interventions on carotid IMT in pediatric obesity (6–18-year-olds). Hedges’ g and 95% confidence
intervals (CIs) were calculated.
Results: Six randomized controlled trials (303 youths) were included. Exercise was associated with a small-to-moderate but
significant reduction in carotid IMT (g=-0.306; 95% CI -0.540 to -0.072; p = 0.011). Likewise, exercise program duration per week
significantly influenced the effect of exercise on carotid IMT (b=-0.060; p = 0.015).
Conclusions: Exercise seems to reduce carotid IMT in childhood obesity. Therefore, encouraging obese pediatric individuals to
become physically active can lead to favorable changes in the arterial wall.