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        • Universidad Jorge Tadeo Lozano (Colombia)
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        • Universidad Jorge Tadeo Lozano (Colombia)
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        Low performance of rapid antigen detection test as frontline testing for COVID-19 diagnosis

        Registro en:
        1386-6532
        https://doi.org/10.1016/j.jcv.2020.104455
        http://hdl.handle.net/20.500.12010/10515
        https://doi.org/10.1016/j.jcv.2020.104455
        http://repositorioslatinoamericanos.uchile.cl/handle/2250/3499849
        Autor
        Scohy, Anaïs
        Anantharajah, Ahalieyah
        Bodéus, Monique
        Kabamba-Mukadi, Benoît
        Verroken, Alexia
        Rodriguez-Villalobos, Hector
        Institución
        • Universidad Jorge Tadeo Lozano (Colombia)
        Resumen
        Background: Ensuring accurate diagnosis is essential to limit the spread of SARS-CoV-2 and for the clinical management of COVID-19. Although real-time reverse transcription polymerase chain reaction (RT- qPCR) is the current recommended laboratory method to diagnose SARS-CoV-2 acute infection, several factors such as requirement of special equipment and skilled staff limit the use of these time-consuming molecular techniques. Recently, several easy to perform rapid antigen detection tests were developed and recommended in some countries as the first line of diagnostic. Objectives: The aim of this study was to evaluate the performances of the Coris COVID-19 Ag Respi-Strip test, a rapid immunochromatographic test for the detection of SARS-CoV-2 antigen, in comparison to RT-qPCR. Results: 148 nasopharyngeal swabs were tested. Amongst the 106 positive RT-qPCR samples, 32 were detected by the rapid antigen test, given an overall sensitivity of 30.2%. All the samples detected positive with the antigen rapid test were also positive with RT-qPCR. Conclusions: Higher viral loads are associated with better antigen detection rates. Unfortunately, the overall poor sensitivity of the COVID-19 Ag Respi-Strip does not allow using it alone as the frontline testing for COVID-19 diagnosis.
        Materias
        COVID-19
        Rapid antigen detection test
        SARS-CoV-2

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        Red de Repositorios Latinoamericanos
        + de 8.000.000 publicaciones disponibles
        500 instituciones participantes
        Dirección de Servicios de Información y Bibliotecas (SISIB)
        Universidad de Chile
        Ingreso Administradores
        Colecciones destacadas
        • Tesis latinoamericanas
        • Tesis argentinas
        • Tesis chilenas
        • Tesis peruanas
        Nuevas incorporaciones
        • Argentina
        • Brasil
        • Colombia
        • México
        Dirección de Servicios de Información y Bibliotecas (SISIB)
        Universidad de Chile
        Red de Repositorios Latinoamericanos | 2006-2018