| dc.description.abstract | SARS-CoV-2 infection associated respiratory disease- COVID-19 has evolved into a
pandemic but, being a new form of virus, pathogenesis of disease causation is not fully
understood and drugs and vaccines against this virus are still being tested so that no effective
drugs or vaccines have been advised by regulatory authority. In this context, the Ministry of
AYUSH, Government of India has recommended ‘Ayush Kwath’ to improve the immunity
and combat the infection. Our objective of this literature review is to review the role of
immunity in pathogenesis of COVID-19 and role of Ayush Kwath against the virus and
regulation of immunity. Current review was conducted using a search of available literature
on COVID-19 and immunity, Vyadhikshamatwa, Ayurveda and COVID-19, Rasayana,
Coronavirus, SARS-CoV-2, immunomodulatory effects of medicinal plants; Tulsi/ Holy
Basil/ Ocimum sanctum, Dalchini /Cinnamon/ Cinnamomum zeylanicum, Sunthi/ Ginger/
Zingiber officinale and Marich/ Black Pepper/ Piper nigrum. Ayurveda, being an ancient
science have both medicinal and cultural values and had stimulated our kitchen and
influenced what we ate in different seasons and the remedies we used for common ailments.
Herbs such as Tulsi, Marich, Sunthi, Dalchini are the most commonly used and easily
available drugs in home. Thus, Ayush Kwath due to its immune-modulatory, antiviral, antioxidant, anti-inflammatory, anti-platelet, anti-atherosclerotic, hepato-protective, renoprotective properties; seems to be effective in immuno-regulation for controlling viral
infections like COVID-19. Further pre-clinical and clinical trials need to be done for the
evaluation of safety and efficacy of this polyherbal formulation. | |
