Participación de la corteza infralímbica en la tarea de discriminación simple de olores en ratas

bachelorThesis

Fecha

2014-04-24

Registro en:

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http://hdl.handle.net/10818/10359

259254

TE06401

http://repositorioslatinoamericanos.uchile.cl/handle/2250/3474821

Autor

Quiroz Padilla, María Fernanda

Institución

Universidad de la Sabana (Colombia)

Resumen

Este estudio evaluó la participación de la corteza infralímbica (IL) en los procesos del aprendizaje y reaprendizaje de ratas Wistar en la tarea de discriminación simple de olores. Para el logro de dicho objetivo, se realizaron lesiones bilaterales pre-entrenamiento con N-metil-D-Aspartato (NMDA) en la IL y se analizó el desempeño de los sujetos en la tarea de discriminación simple de olores (DSO) teniendo en cuenta la latencia (tiempo que tarda el animal en encontrar el reforzador en el aroma asociado), los errores (número de veces en que el animal busca el reforzador en el aroma que no ha sido asociado al refuerzo) y las omisiones (número de veces en que el animal se acerca al aroma correcto y no accede al reforzador). Los resultados muestran que en los tres primeros ensayos de la fase de adquisición, las ratas con lesión presentaron una latencia mayor que el grupo control vehículo ensayo 1: (P= 0.000); ensayo 2: (P= 0.022); ensayo 3: (P= 0.022), igualmente, presentaron un mayor número de errores y omisiones en el primer ensayo (P=0,000). Nota: Para consultar la carta de autorización de publicación de este documento por favor copie y pegue el siguiente enlace en su navegador de internet: http://hdl.handle.net/10818/10360

Materias

Experimentos en ratones -- Colombia

Ratones -- Génetica

Olfato -- Olores

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