Cloud computing datacenters currently provide millions of virtual machines in highly dynamic Infrastructure as a Service (IaaS) markets. As a first step on implementing algorithms previously proposed by the authors for Virtual Machine Placement (VMP) in a real- world IaaS middleware, this work presents an experimental comparison of these algorithms against current algorithms considered for solving VMP problems in OpenStack. Several experiments considering scenario- based simulations for uncertainty modelling demonstrate that the proposed algorithms present promising results for its implementation towards real-world operations. Next research steps are also summarized.Facultad de Informática