dc.contributorUniversidade Federal de São Paulo (UNIFESP)
dc.creatorFrizon, Luciana
dc.creatorAraujo, Marilia Cavalcante
dc.creatorAndrade, Larissa
dc.creatorYu, Maria Cecilia Zorat
dc.creatorWakamatsu, Tais Hitomi
dc.creatorHofling-Lima, Ana Luisa
dc.creatorGomes, José Álvaro Pereira
dc.date.accessioned2015-06-14T13:46:58Z
dc.date.accessioned2019-05-24T17:17:30Z
dc.date.available2015-06-14T13:46:58Z
dc.date.available2019-05-24T17:17:30Z
dc.date.created2015-06-14T13:46:58Z
dc.date.issued2014-03-01
dc.identifierClinics. Faculdade de Medicina / USP, v. 69, n. 3, p. 168-172, 2014.
dc.identifier1807-5932
dc.identifier1980-5322
dc.identifierhttp://repositorio.unifesp.br/handle/11600/8259
dc.identifierS1807-59322014000300168.pdf
dc.identifierS1807-59322014000300168
dc.identifier10.6061/clinics/2014(03)04
dc.identifierWOS:000333034000004
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/2827511
dc.description.abstractOBJECTIVE: To determine the conjunctival bacterial flora present in patients with Stevens-Johnson syndrome. METHODS: A prospective study of the conjunctival bacterial flora was performed in 41 eyes of 22 patients with Stevens-Johnson syndrome. The information gathered included the patient's sex and age, the duration of disease, the cause of Stevens-Johnson syndrome, and treatments. Scrapings of the inferior conjunctival fornix were performed in both eyes. Fourteen days before scraping, the patients were asked to interrupt all topical medication and start using 0.5% nonpreserved methylcellulose. The microbiological evaluation included microorganism identification and determination of antibiotic sensitivity. RESULTS: Of 22 patients (41 eyes), 14 (64%) were females, and eight (36%) were males. The mean age was 33.2 years, and the mean duration of disease was 15.6 years. Visual acuity ranged from light perception to 20/25 (1.57 logMar). The treatment received by most patients consisted of tear substitutes, topical antibiotics, and contact lenses. Bacterial identification was positive in 39 eyes (95%) and negative in two eyes (5%). Gram-positive cocci accounted for 55.5% of the microorganisms, whereas gram-positive bacilli and gram-negative bacilli accounted for 19% and 25.5%, respectively. Half of the patients (54%) had multiple bacterial species in their flora, and only one bacterial species was identified in the other half. Resistant bacteria were isolated from four eyes. The antibiotic sensitivity results for the Streptococcus group showed the lowest sensitivity and the highest microbial resistance identified. CONCLUSION: Patients with Stevens-Johnson syndrome have a diverse conjunctival flora that includes many pathogenic species.
dc.languageeng
dc.publisherFaculdade de Medicina / USP
dc.relationClinics
dc.rightsAcesso aberto
dc.subjectConjunctival Flora
dc.subjectMicrobial Sensitivity Tests
dc.subjectStevens-Johnson Syndrome
dc.titleEvaluation of conjunctival bacterial flora in patients with Stevens-Johnson Syndrome
dc.typeArtículos de revistas


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