Analysis and chromosomal mapping of Leishmania (Leishmania) amazonensis amastigote expressed sequence tags

dc.contributorUniversidade Federal de São Paulo (UNIFESP)
dc.creatorGentil, Luciana Girotto [UNIFESP]
dc.creatorLasakosvitsch, Fernanda [UNIFESP]
dc.creatorFranco da Silveira, José [UNIFESP]
dc.creatorSantos, Márcia Regina Machado dos [UNIFESP]
dc.creatorBarbiéri, Clara Lúcia [UNIFESP]
dc.date.accessioned2015-06-14T13:37:04Z
dc.date.available2015-06-14T13:37:04Z
dc.date.created2015-06-14T13:37:04Z
dc.date.issued2007-09-01
dc.identifierMemórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 102, n. 6, p. 707-711, 2007.
dc.identifier0074-0276
dc.identifierhttp://repositorio.unifesp.br/handle/11600/3894
dc.identifierS0074-02762007000600008.pdf
dc.identifierS0074-02762007000600008
dc.identifier10.1590/S0074-02762007005000065
dc.description.abstractThe characterization of expressed sequence tags (ESTs) generated from a cDNA library of Leishmania (Leishmania) amazonensis amastigotes is described. The sequencing of 93 clones generated new L. (L.) amazonensis ESTs from which 32% are not related to any other sequences in database and 68% presented significant similarities to known genes. The chromosome localization of some L. (L.) amazonensis ESTs was also determined in L. (L.) amazonensis and L. (L.) major. The characterization of these ESTs is suitable for the genome physical mapping, as well as for the identification of genes encoding cysteine proteinases implicated with protective immune responses in leishmaniasis.
dc.languageeng
dc.publisherInstituto Oswaldo Cruz, Ministério da Saúde
dc.relationMemórias do Instituto Oswaldo Cruz
dc.rightsAcesso aberto
dc.subjectLeishmania (Leishmania) amazonensis
dc.subjectamastigotes
dc.subjectcDNA library
dc.titleAnalysis and chromosomal mapping of Leishmania (Leishmania) amazonensis amastigote expressed sequence tags
dc.typeArtigo


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