dc.contributorUniversidade Federal de São Paulo (UNIFESP)
dc.creatorPorcionatto, Marimélia Aparecida [UNIFESP]
dc.creatorNader, Helena Bonciani [UNIFESP]
dc.creatorDietrich, Carl Peter [UNIFESP]
dc.date.accessioned2015-06-14T13:24:52Z
dc.date.available2015-06-14T13:24:52Z
dc.date.created2015-06-14T13:24:52Z
dc.date.issued1999-05-01
dc.identifierBrazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 32, n. 5, p. 539-544, 1999.
dc.identifier0100-879X
dc.identifierhttp://repositorio.unifesp.br/handle/11600/776
dc.identifierS0100-879X1999000500006.pdf
dc.identifierS0100-879X1999000500006
dc.identifier10.1590/S0100-879X1999000500006
dc.identifierWOS:000080489600006
dc.description.abstractHeparan sulfate is a component of vertebrate and invertebrate tissues which appears during the cytodifferentiation stage of embryonic development. Its structure varies according to the tissue and species of origin and is modified during neoplastic transformation. Several lines of experimental evidence suggest that heparan sulfate plays a role in cellular recognition, cellular adhesion and growth control. Heparan sulfate can participate in the process of cell division in two distinct ways, either as a positive or negative modulator of cellular proliferation, or as a response to a mitogenic stimulus.
dc.languageeng
dc.publisherAssociação Brasileira de Divulgação Científica
dc.relationBrazilian Journal of Medical and Biological Research
dc.rightsAcesso aberto
dc.subjectheparan sulfate
dc.subjectglycosaminoglycan
dc.subjectproteoglycan
dc.subjectcell division
dc.subjectcell cycle
dc.subjectgrowth factors
dc.titleHeparan sulfate and cell division
dc.typeArtigo


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