Analysis of the genetic diversity and phylogenetic relationships of putative human papillomavirus types

dc.creatorChouhy, Diego
dc.creatorBolatti, Elisa María
dc.creatorPerez, Germán Roberto
dc.creatorGiri, Adriana Angélica
dc.date2017-12-06T12:13:09Z
dc.date2017-12-06T12:13:09Z
dc.date2013-11
dc.date2017-12-06T12:13:09Z
dc.date2017-12-06T12:13:09Z
dc.date2013-11
dc.date.accessioned2019-05-17T20:22:23Z
dc.date.available2019-05-17T20:22:23Z
dc.identifier0022-1317
dc.identifierhttps://dx.doi.org/10.1099/vir.0.055137-0
dc.identifierhttp://hdl.handle.net/2133/9862
dc.identifierhttp://hdl.handle.net/2133/9862
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/2679655
dc.descriptionMore than 170 human papillomavirus (HPV) types have been completely sequenced, curated and divided into five genera: Alphapapillomavirus, Betapapillomavirus, Gammapapillomavirus, Mupapillomavirus and Nupapillomavirus. With the application of PCR methods, hundreds of putative novel HPV types have been identified as PCR amplicons in mucosa and skin. However, at present there are no studies reporting a systematic search of the currently known L1 amplicons and their phylogenetic relationships. This survey revealed the existence of at least 202 different putative HPV types that are pending for full-genome characterization: five alphapapillomaviruses, 37 betapapillomaviruses, 159 gammapapillomaviruses and one mupapillomavirus. All potential viruses of the genera Alphapapillomavirus and Betapapillomavirus were grouped in the defined species, while 59 putative gammapapillomaviruses types were segregated in 21 unidentified putative species. These data highlight the need for progress in the identification of additional taxa of the family Papillomaviridae in order to elucidate the diversity, evolution and medical implications of these viruses.
dc.descriptionFil: Chouhy, Diego. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Area Virología; Argentina
dc.descriptionFil: Chouhy, Diego. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario (UNR-CONICET); Argentina
dc.descriptionFil: Bolatti, Elisa María. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario (UNR-CONICET); Argentina
dc.descriptionFil: Germán R. Pérez. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Area Virología; Argentina
dc.descriptionFil: Germán R. Pérez. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario (UNR-CONICET); Argentina
dc.descriptionFil: Giri, Adriana Angélica. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Area Virología; Argentina
dc.descriptionFil: Giri, Adriana Angélica. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario (UNR-CONICET); Argentina
dc.formatapplication/pdf
dc.languageeng
dc.relationhttps://dx.doi.org/10.1099/vir.0.055137-0
dc.relationhttp://jgv.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.055137-0
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.rightsMicrobiology Society
dc.rightsChouhy, Diego
dc.rightsBolatti, Elisa María
dc.rightsPérez, Germán R.
dc.rightsGiri, Adriana Angélica
dc.rightsopenAccess
dc.subjectHuman papillomavirus
dc.subjectPutative types
dc.subjectDiversity
dc.titleAnalysis of the genetic diversity and phylogenetic relationships of putative human papillomavirus types


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