| dc.creator | Teijeiro, Juan Manuel | |
| dc.creator | Munuce, María José | |
| dc.creator | Caille, Adriana María | |
| dc.creator | Zumoffen, Carlos | |
| dc.creator | Marini, Patricia Estela | |
| dc.date | 2017-11-10T20:38:15Z | |
| dc.date | 2017-11-10T20:38:15Z | |
| dc.date | 2017-07-07 | |
| dc.date | 2017-11-10T20:38:15Z | |
| dc.date | 2017-11-10T20:38:15Z | |
| dc.date | 2017-07-07 | |
| dc.date.accessioned | 2019-05-17T20:22:04Z | |
| dc.date.available | 2019-05-17T20:22:04Z | |
| dc.identifier | 2167-0250 | |
| dc.identifier | http://hdl.handle.net/2133/9267 | |
| dc.identifier | http://hdl.handle.net/2133/9267 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/2679595 | |
| dc.description | Innovative methods to select sperm subpopulations with the best fertilizing ability are needed in assisted
reproductive techniques (ART) in order to improve fertilization and pregnancy rates, while also considering possible
epigenetic effects on the offspring. Molecular based selection methods are searched for, under the premise that they
could be an improvement over classical selection by morphology and movement. One of these methods sustains the
elimination of sperm that can bind to annexin A5 (ANX V), coupled to paramagnetic beads, through the
phosphatidyl-serine exposed on their membranes upon apoptosis. Although reports accumulate about the use of this method, controversy persists as to the benefits of ANX V based sperm selection in ART. In this review we consider the arguments in favour and against this method and conclude that to the moment the evidence does not support MACS regular use in ART. | |
| dc.description | Fil: Munuce, María José. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Laboratorio de Medicina Reproductiva; Argentina. | |
| dc.description | Fil: Teijeiro, Juan Manuel. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Laboratorio de Medicina Reproductiva; Argentina. | |
| dc.description | Fil: Caille, Adriana María. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Laboratorio de Medicina Reproductiva; Argentina. | |
| dc.description | Fil: Zumoffen, Carlos. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Laboratorio de Medicina Reproductiva; Argentina. | |
| dc.description | Fil: Marini, Patricia Estela. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Laboratorio de Medicina Reproductiva; Argentina. | |
| dc.format | application/pdf | |
| dc.language | eng | |
| dc.publisher | OMICS International | |
| dc.relation | https://www.omicsonline.org/open-access/use-of-annexin-v-based-sperm-selection-in-assisted-reproduction-2167-0250-1000182.php?aid=90816 | |
| dc.rights | http://creativecommons.org/publicdomain/zero/1.0/ | |
| dc.rights | Marini, Patricia Estela | |
| dc.rights | Teijeiro, Juan Manuel | |
| dc.rights | Munuce, María José | |
| dc.rights | Caille, Adriana María | |
| dc.rights | Zumoffen, Carlos | |
| dc.rights | openAccess | |
| dc.subject | Anexina A5 | |
| dc.subject | selección de espermatozoides | |
| dc.subject | técnicas de reproducción asistida | |
| dc.subject | Annexin A5 | |
| dc.subject | Sperm selection | |
| dc.subject | Assisted reproductive techniques | |
| dc.title | Use of Annexin V based Sperm Selection in Assisted Reproduction | |
| dc.type | Artículos de revistas | |
| dc.type | Artículos de revistas | |
| dc.type | Artículos de revistas | |
