Day/night melatonin content in cerebral palsy

dc.contributorSpecialized Center for Rehabilitation
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorUniversity of Marília–UNIMAR
dc.date.accessioned2018-12-11T17:38:26Z
dc.date.available2018-12-11T17:38:26Z
dc.date.created2018-12-11T17:38:26Z
dc.date.issued2018-11-01
dc.identifierNeuroscience Letters, v. 686, p. 23-27.
dc.identifier1872-7972
dc.identifier0304-3940
dc.identifierhttp://hdl.handle.net/11449/180163
dc.identifier10.1016/j.neulet.2018.08.045
dc.identifier2-s2.0-85052954563
dc.identifier2-s2.0-85052954563.pdf
dc.identifier8372363591179624
dc.description.abstractChanges in the sleep-wake cycle are frequent and may impair quality of life in individuals with cerebral palsy (CP). To investigate if a lack of a day/night variation of melatonin content could be related with sleep disorders (SD), the SD were evaluated with a Sleep Questionnaire and the melatonin content using ELISA in 33 individuals with CP and 24 controls. The indicative of SD were present in 47% of CP group, and the most frequent was the indicative of sleep breathing disorder. The CP group showed higher diurnal and lower nocturnal melatonin content than controls. Individuals with CP that had indicative of SD showed lower nocturnal content of melatonin than those without SD. These results showed that the lack of the day/night variation of melatonin was related to SD in individuals with CP.
dc.languageeng
dc.relationNeuroscience Letters
dc.relation0,946
dc.rightsAcesso aberto
dc.sourceScopus
dc.subjectBehavior
dc.subjectCerebral palsy
dc.subjectMelatonin
dc.subjectNeurodevelopment
dc.subjectSleep
dc.titleDay/night melatonin content in cerebral palsy
dc.typeArtículos de revistas


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