dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorFAM
dc.date.accessioned2018-12-11T17:22:02Z
dc.date.available2018-12-11T17:22:02Z
dc.date.created2018-12-11T17:22:02Z
dc.date.issued2018-08-01
dc.identifierToxins, v. 10, n. 8, 2018.
dc.identifier2072-6651
dc.identifierhttp://hdl.handle.net/11449/176679
dc.identifier10.3390/toxins10080305
dc.identifier2-s2.0-85051076829
dc.identifier2-s2.0-85051076829.pdf
dc.description.abstractAlthough systemic reactions caused by allergenic proteins present in venoms affect a small part of the world population, Hymenoptera stings are among the main causes of immediate hypersensitivity responses, with risk of anaphylactic shock. In the attempt to obtain therapeutic treatments and prophylaxis to hypersensitivity responses, interest in the molecular characterization of these allergens has grown in the scientific community due to the promising results obtained in immunological and clinical studies. The present review provides an update on the knowledge regarding the immune response and the therapeutic potential of Antigen 5 derived from Hymenoptera venom. The results confirm that the identification and topology of epitopes, associated with molecular regions that interact with antibodies, are crucial to the improvement of hypersensitivity diagnostic methods.
dc.languageeng
dc.relationToxins
dc.relation0,955
dc.rightsAcesso aberto
dc.sourceScopus
dc.subjectAnaphylaxis
dc.subjectAntigen 5
dc.subjectHymenoptera
dc.subjectHypersensitivity
dc.subjectImmune response
dc.titleCurrent advances in immunological studies on the vespidae venom antigen 5: Therapeutic and prophylaxis to hypersensitivity responses
dc.typeOtros


Este ítem pertenece a la siguiente institución