dc.contributorUniversity of Nebraska-Lincoln
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-12-11T17:20:49Z
dc.date.available2018-12-11T17:20:49Z
dc.date.created2018-12-11T17:20:49Z
dc.date.issued2018-01-01
dc.identifierAdvances in Experimental Medicine and Biology, v. 1055, p. 101-110.
dc.identifier2214-8019
dc.identifier0065-2598
dc.identifierhttp://hdl.handle.net/11449/176444
dc.identifier10.1007/978-3-319-90143-5_5
dc.identifier2-s2.0-85048436175
dc.description.abstractMetallomics allows the integration of traditionally analytical studies with inorganic and biochemical studies. The study of metallomics in living organisms allows us to obtain information about how the metal ion is distributed and coordinated with proteins, the essentiality and/or toxicity, and the individual concentrations of metal species, thus contributing to elucidation of the physiological and functional aspects of these biomolecules. In this context, several lines of research have appeared in the literature with different terms and approaches. For example, metallomic, which deals with the characterization of the total metal/metalloid species present in an organism; metalloprotein, which deals with the characterization of the total elements present in a specific site of an organism (cellular behavior, protein, metalloprotein); and metallomic, which deals with a more in-depth study of metallome. In this area, information is sought on the interactions and functional connections of metal/metalloid species with genes, proteins, metabolites and other biomolecules of the organism and, therefore, the elucidation of the biological role exerted by the metal ions bound to the biomolecules. In this chapter, we will describe techniques used in animal studies.
dc.languageeng
dc.relationAdvances in Experimental Medicine and Biology
dc.relation0,867
dc.rightsAcesso restrito
dc.sourceScopus
dc.subjectAnimal
dc.subjectFish
dc.subjectMetallomic
dc.subjectMetalloprotein
dc.titleMetallomics in Fish
dc.typeCapítulos de libros


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