Anti-inflammatory and antiproliferative activities of Ixora brevifolia Benth. (Rubiaceae)

dc.contributorUniversidade Estadual de Maringá (UEM)
dc.contributorUniversidade Federal de Goiás (UFG)
dc.contributorUniversidade Estadual de Campinas (UNICAMP)
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-12-11T17:12:53Z
dc.date.available2018-12-11T17:12:53Z
dc.date.created2018-12-11T17:12:53Z
dc.date.issued2018-06-03
dc.identifierNatural Product Research, v. 32, n. 11, p. 1357-1360, 2018.
dc.identifier1478-6427
dc.identifier1478-6419
dc.identifierhttp://hdl.handle.net/11449/174792
dc.identifier10.1080/14786419.2017.1344654
dc.identifier2-s2.0-85021184727
dc.identifier2-s2.0-85021184727.pdf
dc.description.abstractThe crude extract and fractions from the branches of Ixora brevifolia, a tree found in the Brazilian Cerrado, were tested for anti-inflammatory and in vitro antiproliferative effects. The crude extract and n-hexane fraction exhibited significant inhibition of ear oedema in mice, while n-hexane-precipitated and chloroform fractions strongly inhibited the myeloperoxidase activity in ear tissue. The n-hexane and n-hexane-precipitated fractions showed strong growth inhibition for glioma cell line and the hydromethanolic fraction inhibited the growth of leukaemia cell line.
dc.languageeng
dc.relationNatural Product Research
dc.relation0,671
dc.rightsAcesso aberto
dc.sourceScopus
dc.subjectanti-inflammatory activity
dc.subjectantiproliferative activity
dc.subjectIxora brevifolia
dc.subjectRubiaceae
dc.titleAnti-inflammatory and antiproliferative activities of Ixora brevifolia Benth. (Rubiaceae)
dc.typeArtículos de revistas


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