dc.contributor | Universidade Estadual Paulista (Unesp) | |
dc.date.accessioned | 2018-12-11T17:12:40Z | |
dc.date.available | 2018-12-11T17:12:40Z | |
dc.date.created | 2018-12-11T17:12:40Z | |
dc.date.issued | 2017-01-01 | |
dc.identifier | Acta Cirurgica Brasileira, v. 32, n. 5, p. 388-395, 2017. | |
dc.identifier | 1678-2674 | |
dc.identifier | 0102-8650 | |
dc.identifier | http://hdl.handle.net/11449/174741 | |
dc.identifier | 10.1590/s0102-865020170050000008 | |
dc.identifier | S0102-86502017000500388 | |
dc.identifier | 2-s2.0-85020451801 | |
dc.identifier | S0102-86502017000500388.pdf | |
dc.description.abstract | Purpose: To evaluate DNA damage levels in pregnant rats undergoing a treadmill exercise program. Methods: Wistar Kyoto rats were allocated into two groups (n= 5 animals/group): non-exercise and exercise. The pregnant rats were underwent an exercise protocol on a treadmill throughout pregnancy. Exercise intensity was set at 50% of maximal capacity during maximal exercise testing performed before mating. Body weight, blood pressure and glucose levels, and triglyceride concentration were measured during pregnancy. At day 10 post-natal, the animals were euthanized and maternal blood samples were collected for DNA damage. Results: Blood pressure and glucose levels and biochemical measurements showed no significant differences. Increased DNA damage levels were found in exercise group compared to those of non-exercise group (p<0.05). Conclusion: The exercise intensity protocol used in the study might have been exhaustive leading to maternal increased DNA damage levels, demonstrating the relevance of an adequate protocol of physical exercise. | |
dc.language | eng | |
dc.relation | Acta Cirurgica Brasileira | |
dc.relation | 0,395 | |
dc.rights | Acesso aberto | |
dc.source | Scopus | |
dc.subject | DNA damage | |
dc.subject | Exercise | |
dc.subject | Pregnancy | |
dc.subject | Rats | |
dc.title | DNA damage in wistar kyoto rats exercised during pregnancy | |
dc.type | Artículos de revistas | |