Rietveld method in the analysis of polymorphism in mebendazole tablets acquired in Brazil's drugstores

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorUniversidade Federal do ABC (UFABC)
dc.date.accessioned2018-12-11T16:58:22Z
dc.date.available2018-12-11T16:58:22Z
dc.date.created2018-12-11T16:58:22Z
dc.date.issued2015-09-01
dc.identifierJournal of the Brazilian Chemical Society, v. 26, n. 9, p. 1760-1768, 2015.
dc.identifier1678-4790
dc.identifier0103-5053
dc.identifierhttp://hdl.handle.net/11449/172068
dc.identifier10.5935/0103-5053.20150151
dc.identifierS0103-50532015000901760
dc.identifier2-s2.0-84941564408
dc.identifierS0103-50532015000901760.pdf
dc.description.abstractMebendazole (MBZ) is an anthelmintic medicine known to exhibit the polymorphs A, B and C, where polymorph C is the one indicated for tablets. Mebendazole commercial tablets (references, generics and similars) were analyzed in this work using X-ray powder diffraction data and the Rietveld method (RM) aiming at characterizing and quantifying crystal phases. Form C was found in mixture with form A in formulations of 500 mg (reference and generic). One of the generics presented a batch with form B and another one with form C. All the other tablets presented form A.
dc.languageeng
dc.relationJournal of the Brazilian Chemical Society
dc.relation0,357
dc.relation0,357
dc.rightsAcesso aberto
dc.sourceScopus
dc.subjectMebendazole
dc.subjectPolymorphism
dc.subjectRietveld method
dc.subjectX-ray powder diffractometry
dc.titleRietveld method in the analysis of polymorphism in mebendazole tablets acquired in Brazil's drugstores
dc.typeArtículos de revistas


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