A systematic and critical review on bioanalytical method validation using the example of simultaneous quantitation of antidiabetic agents in blood

dc.contributorUniversidade Federal do Paraná (UFPR)
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-12-11T16:47:03Z
dc.date.available2018-12-11T16:47:03Z
dc.date.created2018-12-11T16:47:03Z
dc.date.issued2017-06-15
dc.identifierJournal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, v. 1055-1056, p. 61-71.
dc.identifier1873-376X
dc.identifier1570-0232
dc.identifierhttp://hdl.handle.net/11449/169661
dc.identifier10.1016/j.jchromb.2017.04.024
dc.identifier2-s2.0-85018463022
dc.identifier2-s2.0-85018463022.pdf
dc.description.abstractA systematic and critical review was conducted on bioanalytical methods validated to quantify combinations of antidiabetic agents in human blood. The aim of this article was to verify how the validation process of bioanalytical methods is performed and the quality of the published records. The validation assays were evaluated according to international guidelines. The main problems in the validation process are pointed out and discussed to help researchers to choose methods that are truly reliable and can be successfully applied for their intended use. The combination of oral antidiabetic agents was chosen as these are some of the most studied drugs and several methods are present in the literature. Moreover, this article may be applied to the validation process of all bioanalytical
dc.languageeng
dc.relationJournal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
dc.relation0,805
dc.rightsAcesso aberto
dc.sourceScopus
dc.subjectAntidiabetic agents
dc.subjectBioanalytical method
dc.subjectSystematic review
dc.subjectValidation
dc.titleA systematic and critical review on bioanalytical method validation using the example of simultaneous quantitation of antidiabetic agents in blood
dc.typeOtros


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