Acute lymphoblastic leukemia: Primary bone manifestation with hypercalcemia in a child

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-12-11T16:46:28Z
dc.date.available2018-12-11T16:46:28Z
dc.date.created2018-12-11T16:46:28Z
dc.date.issued2017-01-01
dc.identifierJornal Brasileiro de Patologia e Medicina Laboratorial, v. 53, n. 1, p. 61-64, 2017.
dc.identifier1678-4774
dc.identifier1676-2444
dc.identifierhttp://hdl.handle.net/11449/169566
dc.identifier10.5935/1676-2444.20170010
dc.identifierS1676-24442017000100061
dc.identifier2-s2.0-85015962367
dc.identifierS1676-24442017000100061.pdf
dc.description.abstractPrimary bone manifestation associated with hypercalcemia is an infrequent presentation of acute lymphoblastic leukemia (ALL) in children. An 8-year-old girl was admitted with bone and abdomen pain, vomiting, fever, headache, anemia, elevated serum calcium and normal parathyroid hormone levels. Bone radiographs: osteolytic lesions. Bone marrow biopsy showed an infiltration by ALL with immunohistochemical positivity for CD45, CD20, CD79a, TdT and CD10, clinically characterized by hypercalcemia, multifocal osteolytic lesions and single cytopenia. Bone marrow biopsy was a relevant aid in establishing the diagnosis of multifocal osteolytic lesions, associated with hypercalcemia.
dc.languageeng
dc.relationJornal Brasileiro de Patologia e Medicina Laboratorial
dc.relation0,143
dc.rightsAcesso aberto
dc.sourceScopus
dc.subjectBone marrow
dc.subjectHypercalcemia
dc.subjectPrecursor B-cell lymphoblastic leukemia-lymphoma
dc.titleAcute lymphoblastic leukemia: Primary bone manifestation with hypercalcemia in a child
dc.typeArtículos de revistas


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